Homo sapiens - 638856, 638858, 638861, 638862, 638863, 638865, 638869, 664551, 666418, 680926, 681015, 681037, 697184, 697240, 697382, 700945, 707105, 708281, 709217, 709220, 710036, 718177, 718320, 718433, 731689, 732187, 732669, 732703, 752903, 752988, 755059, 755097 Saccharomyces cerevisiae - 638856, 638857, 638858, 638859, 638862, 638864, 638868, 664544, 665495, 666918, 682065, 699095, 700098, 708282, 718037, 718177, 731698, 732505, 732670, 753353, 754237, 755059 Schizosaccharomyces pombe - 638856, 638858, 638862, 664552, 664744, 665049, 666177, 666436, 697171, 754237 Caenorhabditis elegans - 638859, 679433, 708239, 753353, 754237, 755059, 755087 Drosophila melanogaster separase is required for sister chromatid separation in mitosis 638860 Drosophila melanogaster - 638862, 754237, 755061 Xenopus laevis - 638862, 682062 Saccharomyces cerevisiae separase is part of the so called Cdc fourteen anaphase release network, that promotes Cdc14 release from the nucleolus during early anaphase 638866 Saccharomyces cerevisiae separase mediates Cdc14 release from nucleoli during meiosis through a mechanism that is indepenent of its protease activity 638867 Xenopus sp. - 664553, 666319 Mus musculus - 664545, 664676, 665797, 681037, 682065, 682481, 700096, 700165, 700945, 718177, 731697, 752903 Drosophila sp. (in: flies) - 665802, 754836 Danio rerio - 680013 Anaplasma marginale several strains 698110 Saccharomyces cerevisiae commercial baker's yeast 698119 Trypanosoma brucei - 700280 Saccharomyces cerevisiae SK1 - 708282 Arabidopsis thaliana ecotype Columbia 708285 Arabidopsis thaliana - 666581, 710317, 754237, 755059 Arabidopsis thaliana ESP; gene AtESP 718194 Caenorhabditis elegans gene Sep-1 718194 Chlamydomonas reinhardtii gene ESP1 718194 Cryptosporidium muris gene Separase 718194 Drosophila melanogaster gene Sse/THR, Drosophila separase is encoded by two different genes: (1) Sse-encoding separase-like protein with protease domain and (2) THR (three rows) for the protein interacting with PIM (pimples), a securin homologue of Drosophila 718194 Homo sapiens gene hESP 718194 Oryza sativa gene Os02g0770700 718194 Ricinus communis gene Separase 718194 Saccharomyces cerevisiae gene ESP1 718194 Schizosaccharomyces pombe gene Cut1 718194 Sorghum bicolor gene XM_002454579 718194 Vitis vinifera gene LOC100259948 718194 Thermochaetoides thermophila - 753353, 754886 Thermochaetoides thermophila DSM 1495 - 753353, 754886 Picea abies - 754237 Schizosaccharomyces pombe ATCC 24843 - 754237 Saccharomyces cerevisiae ATCC 204508 - 755059