3.6.1.56 medicine increased amounts of 8-oxoguanine in the RNA, and decreased expression of MTH1 are observed in the hippocampi of patients suffering from Alzheimer's disease 716343 3.6.1.56 medicine measurements of 8-oxo-dGTPase activity in brains, testes and kidneys may serve as a rough indicator rather than a quantifiable marker of radiation-induced oxidative stress 716889