3.4.22.43	diagnostics	the enzyme is a potential marker for certain colon tumors and breast cancer	668763	
3.4.22.43	medicine	mammalian protease cathepsin V is a therapeutic target to inhibit TLR4-mediated inflammation induced by extracellular high-mobility group box 1 (HMGB1) (disulfide form). HMGB1 (disulfide form), via activation of toll-like receptor 4 (TLR4)-dependent signaling, is a strong driver of pathologic inflammation in both acute and chronic conditions. The mechanism of action involves a direct interaction between cathepsin V with TLR4 and its adaptor protein MyD88	754753	
3.4.22.43	medicine	studies on the role of cathepsin V and cystatin C in the pathophysiology aortic stenosis	683107