1.1.1.3	agriculture	enzyme HSD is used in the development of pesticides	-, 761687	
1.1.1.3	drug development	HSD is an interesting metabolic target in the search for drugs with selective antifungal action and low toxicity to the host	-, 761712	
1.1.1.3	drug development	the enzyme might be a good target for anti-fungal drug development	-, 740860	
1.1.1.3	additional information	HOM6 deletion reduces Candida albicans cell adhesion to polystyrene, which is a common plastic used in many medical devices	-, 740860	
1.1.1.3	pharmacology	enzyme is a target for inhibitor design for construction of antimicrobial agents	654955	
1.1.1.3	synthesis	contrary to wild-type MGA3 cells that secrete 0.4 g/l L-lysine and 59 g/l L-glutamate under optimised fed batch methanol fermentation, the hom-1 mutant M168-20 secretes 11 g/l L-lysine and 69 g/l of L-glutamate. Overproduction of pyruvate carboxylase and its mutant enzyme P455S in M168-20 has no positive effect on the volumetric L-lysine yield and the L-lysine yield on methanol, and causes significantly reduced volumetric L-glutamate yield and L-glutamate yield on methanol	-, 710978	
1.1.1.3	synthesis	enzyme HSD is utilized in the large scale production of L-lysine	-, 761687