4.1.1.15 L-Glu rate-limiting enzyme involved in the synthesis of gamma-aminobutyric acid 4.1.1.15 L-Glu production of 4-aminobutanoate, which is the major inhibitory neurotransmitter in the mammalian brain 4.1.1.15 L-Glu isoenzyme GAD2 may play a unique role in nitrogen metabolism 4.1.1.15 L-Glu the enzyme is under the control of the asexual developmental cycle 4.1.1.15 L-glutamate - 4.1.1.15 L-glutamate GAD is the key enzyme of GABA synthesis, alterations of GABAergic neurotransmission are assumed to play a crucial role in the pathophysiology of mood disorders, overview. Increased relative density of GAD-immunoreactive neuropil, suggests the diathesis of GABAergic system specific for depressed suicidal patients 4.1.1.15 L-glutamate GAD is the rate-limiting enzyme for GABA biosynthesis 4.1.1.15 L-glutamate GAD is the rate-limiting enzyme in controlling GABA synthesis, GABA is synthesized by GAD67 is used for the other functions such as trophic factor for neuronal development or energy source. GAD67 is constitutively active and is responsible for the basal GABA production 4.1.1.15 L-glutamate GAD is the rate-limiting enzyme in controlling GABA synthesis, GABA is synthesized by GAD67 is used for the other functions such as trophic factor for neuronal development or energy source. GAD67 is constitutively active and is responsible for the basal GABA production while GAD65 is transiently activated in response to the extra demand of GABA in neurotransmission 4.1.1.15 L-glutamate GAD is the rate-limiting enzyme in controlling GABA synthesis, GAD65 is transiently activated in response to the extra demand of GABA in neurotransmission