2.4.1.277 TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + 10-deoxymethynolide - 2.4.1.277 TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + 10-deoxymethynolide DesVII is the glycosyltransferase responsible for the attachment of TDP-D-desosamine to macrolactones of varied ring sizes. The enzyme is involved in the biosynthesis of methymycin, neomethymycin, narbomycin, and pikromycin in Streptomyces venezuelae 2.4.1.277 TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + 10-deoxymethynolide the enzyme is involved in biosynthesis of macrolide antibiotics 2.4.1.277 TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + narbonolide - 2.4.1.277 TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + narbonolide the enzyme is involved in biosynthesis of macrolide antibiotics