2.1.1.157	additional information	the enzyme catalyzes the last 2 steps of betaine synthesis from glycine in a 3-step process	
2.1.1.157	additional information	the enzyme catalyzes the last 2 steps of betaine synthesis from glycine in a 3-step process, betaine is required for balancing osmotic pressure under high salt living conditions	
2.1.1.157	additional information	the enzyme is involved in the alternate biosynthesis of betaine, which is an important osmoprotectant and is synthesized in response to abiotic stress	
2.1.1.157	additional information	the broad substrate methyltransferase, glycine sarcosine dimethylglycine methyltransferase, GSDMT, purified from the halophilic methanoarchaeon Methanohalophilus portucalensis strain FDF1, has been shown to possess glycine N-methyltransferase (GMT), sarcosine N-methyltransferase (SMT) and dimethylglycine N-methyltransferase (DMT) activities. SDMT possesses sarcosine N-methyltransferase (SMT) and dimethylglycine N-methyltransferase (DMT) activities	
2.1.1.157	S-adenosyl-L-methionine + N,N-dimethylglycine	-	
2.1.1.157	S-adenosyl-L-methionine + N,N-dimethylglycine	synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine	
2.1.1.157	S-adenosyl-L-methionine + N-methylglycine	synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine	
2.1.1.157	S-adenosyl-L-methionine + sarcosine	-