1.17.1.4 2 2-hydroxypurine + 2 NAD+ + 2 H2O considerable activity 1.17.1.4 2 hypoxanthine + 2 NAD+ + 2 H2O preferred substrate 1.17.1.4 2-amino-4-hydroxy-pterin + NAD+ + H2O i.e. pterin 1.17.1.4 2-amino-4-hydroxy-pterin + NAD+ + H2O conversion of xanthine dehydrogenase to xanthine oxidase is strongly influenced by in vitro cell culture of alveolar epithelial cells 1.17.1.4 2-amino-4-hydroxy-pterin + NAD+ + H2O 11% of the activity compared to xanthine 1.17.1.4 3 purine + 3 NAD+ + 3 H2O poor substrate 1.17.1.4 6,8-dihydroxypurine + NAD+ + H2O - 1.17.1.4 6,8-dihydroxypurine + O2 - 1.17.1.4 guanine + NAD+ + H2O 81.3% of the activity compared to hypoxanthine 1.17.1.4 hypoxanthine + 2 NAD+ + 2 H2O -