1.16.3.1 4 Fe(II) + 4 H+ + O2 - 1.16.3.1 4 Fe(II) + 4 H+ + O2 the enzyme is required for iron homeostasis. It also plays a major role in maintaining the cuprous/cupric redox balance 1.16.3.1 4 Fe2+ + 4 H+ + O2 - 1.16.3.1 Fe(II) + 4 H+ + O2 - 1.16.3.1 Fe(II) + H+ + O2 - 1.16.3.1 Fe2+ + H+ + O2 - 1.16.3.1 Fe2+ + H+ + O2 iron acquisition pathway 1.16.3.1 Fe2+ + H+ + O2 multicopper oxidase essential for normal iron homeostasis 1.16.3.1 additional information developmental role of enzyme in nervous system organization 1.16.3.1 additional information enzyme is involved in conferring peroxide tolerance to the bacterium