6.3.3.6 ATP + (2S,5S)-5-carboxymethylproline - 6.3.3.6 ATP + (2S,5S)-5-carboxymethylproline the enzyme catalyzes the formation of the beta-lactam ring in (5R)-carbapenem-3-carboxylic acid biosynthesis 6.3.3.6 ATP + (2S,5S)-5-carboxymethylproline the enzyme is involved in the biosynthesis of the carbapenem beta-lactam antibiotic (5R)-carbapen-2-em-3-carboxylate