3.4.22.27	Albumin + H2O	degradation	
3.4.22.27	Collagen + H2O	degradation	
3.4.22.27	Collagen type I + H2O	degradation in plasma membranes	
3.4.22.27	CX3CL1 + H2O	cathepsin S is able to cleave membrane-anchored CX3CL1, releasing a 55-kDa fragment to the medium	
3.4.22.27	Elastin + H2O	degradation	
3.4.22.27	Elastin + H2O	degradation in plasma membranes	
3.4.22.27	Elastin + H2O	elastolytic enzyme activity of cathepsin S in artherosclerotic lesions, degradation of aortic elastin contributing to atherosclerosis and diabetes	
3.4.22.27	elastin + H2O	-	
3.4.22.27	Hemoglobin + H2O	degradation	
3.4.22.27	Ii protein + H2O	degradation