3.1.2.22	palmitoyl-[protein] + H2O	-	
3.1.2.22	additional information	altough the ppt-1 gene is not essential for the animal‘s survival, its mutation results in a mild developmental and reproductive phenotype, affects the number and size of mitochondria and results in an abnormality in mitochondrial morphology	
3.1.2.22	additional information	defect in the palmitoyl-(protein) hydrolase gene causes a neurodegenerative disorder. Depalmitoylation of the still uncharacterized substrate(s) of the enzyme is critical for postnatal development or maintainance of cortical neurons	
3.1.2.22	additional information	depalmitoylation reaction, palmitoylation is the post-translational addition of a palmitate moiety to a cysteine residue through a covalent thioester bond	
3.1.2.22	additional information	enzyme deficiency causes infantile neuronal ceroid lipofuscinosis, the enzyme plays an important role in the development of the CNS	
3.1.2.22	additional information	enzyme deficiency causes progressive neurological and granular osmiophilic deposits, GROD, and infantile neuronal ceroid lipofuscinosis	
3.1.2.22	additional information	enzyme deficiency causes progressive neurological disorder infantile neuronal ceroid lipofuscinosis, INCL	
3.1.2.22	additional information	enzyme deficiency causes progressive neurological disorder infantile neuronal ceroid lipofuscinosis, INCL, a lysosomal storage disorder	
3.1.2.22	additional information	enzyme deficiency causes progressive neurological disorder infantile neuronal ceroid lipofuscinosis, INCL, molecular basis	
3.1.2.22	additional information	enzyme deficiency causes the infantile form of neuronal ceroid lipofuscinosis INCL, a progressive encephalopathyof children