2.7.7.69 GDP-alpha-D-glucose + alpha-D-mannose 1-phosphate - 2.7.7.69 GDP-beta-L-galactose + alpha-D-mannose 1-phosphate - 2.7.7.69 GDP-beta-L-galactose + phosphate enzyme guanylylates a conserved active site His residue with GDP-L-galactose, forming L-galactose 1-phosphate for vitamin C synthesis, and regeneration of the enzyme with phosphate to form GDP