2.1.1.256 S-adenosyl-L-methionine + guanine6 in tRNA the enzyme specifically modifies tRNAPhe at guanosine 6 in the tRNA acceptor stem 2.1.1.256 S-adenosyl-L-methionine + guanine6 in tRNACys Trm14 generates m2G at position 6 in tRNACys 2.1.1.256 S-adenosyl-L-methionine + guanine67 in tRNATrp -