2.1.1.137 additional information As3MT methylates inorganic arsenic and its metabolites 2.1.1.137 additional information enzyme evolutionary analysis 2.1.1.137 additional information genetic susceptibility to arsenic toxicity in Asian is different from Africans and Caucasians, overview 2.1.1.137 additional information the enzyme is responsible for the removal of arsenic as the volatile arsines from the bacteria producing trimethylarsine via successive methylation 2.1.1.137 additional information besides methylarsonate and dimethylarsinate, the enzyme also produces trimethylarsenite and dimethylarsine gases 2.1.1.137 S-adenosyl-L-methionine + arsenite - 2.1.1.137 S-adenosyl-L-methionine + arsenite AS3MT may contribute to variation in arsenic metabolism and, perhaps, arsenic-dependent carcinogenesis in humans 2.1.1.137 S-adenosyl-L-methionine + arsenite hAS3MT is the key enzyme in the pathway for methylation of iAs in human hepatic cells 2.1.1.137 S-adenosyl-L-methionine + arsenite methylation of environmental arsenic by conversion to soluble and gaseous methylated species is a detoxifying process that may contribute to global cycling of arsenic 2.1.1.137 S-adenosyl-L-methionine + arsenite As3MT enzyme is indispensable for conversion of the arsenic metabolites to their corresponding methylated products, metabolism of arsenic proceeds through sequential reduction and oxidative methylation involving several enzymes including the arsenic (+3) methyltransferase, overview