1.1.1.102 (S)-2-amino-1-hydroxyoctadecan-3-one + NADPH enzyme acts at the cytoplasmic side of endoplasmic reticulum 1.1.1.102 2-amino-1-hydroxyoctadecan-3-one + NADPH - 1.1.1.102 3-dehydrosphinganine + NADPH - 1.1.1.102 3-dehydrosphinganine + NADPH the enzyme catalyzes an early step in the sphingolipid biosynthesis, overview 1.1.1.102 3-dehydrosphinganine + NADPH the enzyme is not essential for cell viability, but enzyme-deficient mutants produce lower levels of inositolphosphorylceramides 1.1.1.102 3-oxosphinganine + NADPH + H+ -