3.4.22.43	Elastin + H2O	-	
3.4.22.43	Elastin + H2O	elastin degradation activity leading to loss of elasticity in atherosclerosis	
3.4.22.43	Gelatin + H2O	-	
3.4.22.43	additional information	the corneal enzyme stays within cells and is not secreted, suggesting that components of the corneal epithelium are likely substrates	
3.4.22.43	additional information	the predominant expression in thymus suggests a role in the immune system, the expression in testes suggests a role in fertilization processes, the expression in cancer cells together with its absence in normal cells suggests a role in tumor processes	
3.4.22.43	additional information	the enzyme and inhibitor cystatin M/E are involved in regulation of epidermal differentiation	
3.4.22.43	additional information	the enzyme can stimulate H2O2 production, enzyme expression is increased in keratoconus corneas compared to healthy ones, oxidative stress might be involved in the disorder	
3.4.22.43	additional information	direct interaction of cathepsin V with TLR4 and its adaptor protein MyD88	
3.4.22.43	neuropeptide Y + H2O	-	
3.4.22.43	plasminogen + H2O	-	
3.4.22.43	plasminogen + H2O	capability of recombinant human cathepsin V to hydrolyze plasminogen analyzed, physiological role for cathepsin V related to the control of neovascularization in cornea suggested	
3.4.22.43	plasminogen + H2O	cathepsin V hydrolyzes plasminogen at Phe94-Glu95, Ser358-Thr359, and Val468-Leu469 generating angiostatin-related fragments	
3.4.22.43	proenkephalin + H2O	-