3.4.22.26 factor X + H2O that triggers blood coagulation by directly activating factor X in the absence of factor VII 3.4.22.26 factor X + H2O thiol protease with thrombin-like specificity 3.4.22.26 factor X + H2O factor X-activating cysteine proteinase 3.4.22.26 factor X + H2O - 3.4.22.26 factor X + H2O cleavage of Arg-Ile bond in factor X heavy chain, activation of the coaglutation factor X and thereby activation of the plasma blood clotting cascade 3.4.22.26 factor X + H2O cleavage of Arg-Ile bond, activation of the coaglutation factor X 3.4.22.26 factor X + H2O activation 3.4.22.26 inactive factor X + H2O activation of blood coagulation factor X 3.4.22.26 inactive factor X + H2O activation of blood coagulation factor X, degradation of factor X during 24 h 3.4.22.26 additional information enzyme seems to be regulated allosterically 3.4.22.26 additional information the activity of cancer procoagulant in cases of uterine leiomyomas, overview 3.4.22.26 additional information the enzyme is able to stimulate blood platelet adhesion to fibrinogen and collagen, which can also play a role in metastatic spread of cancer as well as primary tumor growth 3.4.22.26 additional information the enzyme plays a role in pathogenesis of cancer-related thrombosis, the enzyme concentration in serum is positively correlated to fibrinogen concentration, but negatively correlated to free protein S plasma content, determination of prothrobotic parameters and correlation to enzyme activity, overview 3.4.22.26 additional information cancer procoagulant is a cysteine protease acting as an activator of coagulation factor X, the protein activates factor X in the absence of tissue factor and factor VII 3.4.22.26 additional information high level of cancer procoagulant is a risk factor for multiple myeloma 3.4.22.26 additional information rat and human cancer procoagulant activity bind similarly to antiCP antibodies 3.4.22.26 PAR-1 receptor + H2O -