2.4.1.38	additional information	enzyme activity might be involved in apoptotic pathway in hepatocarcinoma cells	
2.4.1.38	additional information	decreasing the expression of GalT V in glioma cells promotes apoptosis, inhibits the invasion and migration and the ability of tumor formation in vivo, and reduces the activation of AKT, the enzyme functions as a glioma growth activator, overview, contribution of GalT V in the activation of AKT and MAPK kinase, contribution of serum or EGF in the transcription regulation of the GalT V gene, overview	
2.4.1.38	additional information	downregulation of the enzyme inhibits CDK11(p58)-mediated apoptosis induced by cycloheximide, while ectopically expressed beta1,4-GT 1 increases CDK11p58-mediated apoptosis	
2.4.1.38	additional information	the cell surface enzyme promotes apoptosis by inhibiting the epidermal growth factor receptor pathway via inhibition of the autophosphorylation of epidermal growth factor receptor especially at Try 1068, mechanism, overview	
2.4.1.38	additional information	the enzyme is involved in regulation of carbohydrate composition of milk during lactation, endocrine enzyme regulation, overview	
2.4.1.38	additional information	the enzyme is part of the endoplasmic reticulum and Golgi glycosylation network, glycosyltransferase metabolism, overview	
2.4.1.38	additional information	tumor beta-1,4-galactosyltransferase IV overexpression is closely associated with colorectal cancer metastasis and poor prognosis, relationships between tumor beta-1,4-GT-IV overexpression and clinicopathologic characteristics, overview	
2.4.1.38	additional information	beta 1,4GalT V galactosylates the beta1,6-GlcNAc branch of N-glycans at the cell surface and of secreted glycoproteins, and functions as a positive regulator in glioma development, overview. As2O3-induced gioma cell apoptosis mechanism involves beta 1,4GalT V inhibition, overview	
2.4.1.38	additional information	beta-1,4-galactosylransferase participates in the synthesis of Galbeta1-4-GlcNac disaccharide unit of glycoconjugates, overview	
2.4.1.38	additional information	beta-1,4-GalT I is a type II membrane-bound glycoprotein, which occurs the plasma membrane of different types of cells where it serves as a cell surface adhesion molecule mediating various cell-cell and cell-matrix interactions such as sperm-egg binding, cell spreading, migration, and neurite outgrowth	
2.4.1.38	additional information	beta-1,4-GalT-I plays a key role in the synthesis of selectin ligands such as sialy Lewis, sLex, and sulfated sLex, overview. beta-1,4-GalT-I may play an important role in the inflammation reaction	
2.4.1.38	additional information	HP0826 is the beta-1,4-galactosyltransferase involved in the biosynthesis of the lipopolysaccharide O-chain backbone of Helicobacter pylori	
2.4.1.38	additional information	LgtB is the beta-1,4-galactosyltransferase involved in the biosynthesis of the lipopolysaccharide O-chain backbone of Helicobacter pylori	
2.4.1.38	additional information	the specific inhibitors of the phosphatidylinositol 3-kinase LY294002 and wortmannin up-regulate beta1,4-galactosyltransferase I and thus sensitize SMMC-7721 human hepatocarcinoma cells to cycloheximide-induced apoptosis, overview	
2.4.1.38	additional information	beta4Gal-T1 participates in the synthesis of Galbeta1-4-GlcNac disaccharide unit of glycoconjugates	
2.4.1.38	UDP-alpha-D-galactose + N-acetyl-beta-D-glucosaminylglycopeptide	-	
2.4.1.38	UDP-galactose + laminin	-	
2.4.1.38	UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide	-	
2.4.1.38	UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide	the enzyme effectively galactosylates the GlcNAcbeta1,6Man arm of the highly branched N-glycans that are characteristic of glioma, overview	
2.4.1.38	UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide	the enzyme transfers galactose from UDP-galactose to N-acetylglucosamine residues of the branched N-linked oligosaccharide chains of glycoproteins	
2.4.1.38	UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides	-	
2.4.1.38	UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides	the enzyme facilitates sperm binding to the oocyte zona pellucida	
2.4.1.38	UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides	enzyme participates in the biosynthesis of the oligosaccharide structures of glycoproteins and glycolipids	
2.4.1.38	UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides	the enzyme is involved in the biosynthesis of a variety of carbohydrate structures in glycoproteins and glycolipids	
2.4.1.38	UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides	the enzyme may be involved in the synthesis of poly-N-acetyllactosamine, lacto-N-neotetraose and probably lacto-N-neotetraosylceramide in addition to the formation of the Galbeta1-4GlcNAc group of glycoprotein sugar chains and lactose	
2.4.1.38	UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides	the soluble enzyme form from the luminal fluid of the epididymis is suggested to play a role on sperm maturation	
2.4.1.38	UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides	enzyme functions in the coordinate biosynthesis of complex oligosaccharides, proposed to function in intercellular recognition and/or adhesion	
2.4.1.38	UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides	the enzyme may be involved in the synthesis of plasma glycoproteins by the liver during secretion, and may possibly be required for secretion of these proteins	
2.4.1.38	UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides	biosynthesis of carbohydrate moieties of glycoproteins and glycolipids, role in intercellular recognition and adhesion	
2.4.1.38	UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides	main enzyme responsible for the transfer of galactose residues from UDPgalactose into terminal N-acetylglucosamine residues of complex-type oligosaccharides in newly synthesized glycoproteins in the Golgi apparatus. Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId, a severe neurologic disease characterized by a hydrocephalus, myopathy and blood-clotting defects	
2.4.1.38	UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides	biosynthesis of keratan sulfate-like polysaccharides