1.14.19.6 oleic acid + ? expression in Saccharomyces cerevisiae leads to endogenous production of linoleic acid 1.14.19.6 oleic acid + ? linoleic acid was detectable when expressing Fm2 in DELTA12 desaturase knockout Yarrowia lipolytica 1.14.19.6 oleic acid + reduced acceptor + O2 specific substrate 1.14.19.6 oleic acid + reduced acceptor + O2 best substrate with 23% conversion 1.14.19.6 oleic acid + reduced acceptor + O2 best substrate with 63.3% conversion 1.14.19.6 oleic acid + reduced acceptor + O2 best substrate with 72% conversion 1.14.19.6 oleoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ - 1.14.19.6 oleoyl-CoA + 2 reduced acceptor + O2 + 2 H+ - 1.14.19.6 oleoyl-CoA + reduced acceptor + O2 the DELTA12 desaturase provides the key step for the cockroach to become nutritionally independent of dietary lipid and to synthesize eicosanoids de novo 1.14.19.6 oleoyl-CoA + reduced acceptor + O2 -