1.3.3.3 Ca2+ 50% activation of anaerobic enzyme at 5 mM 390974 1.3.3.3 Co2+ activation up to 0.1 mM, beyond inhibitory 390978 1.3.3.3 Co2+ optimal activation only for anaerobic enzyme at 0.1 mM 390974 1.3.3.3 Cu2+ 0.06 atom per enzyme 390949 1.3.3.3 Cu2+ 1.05 atoms per enzyme 390949, 390953 1.3.3.3 Cu2+ about 0.03 mol per mol of polypeptide for both enzyme forms 655624 1.3.3.3 Fe2+ 0.07-0.14 atom per enzyme 390949 1.3.3.3 Fe2+ 0.09-1.25 mol per mol of polypeptide for the recombinant wild-type enzyme, 0.2 mol per mol of polypeptide for the selenomethionine-labeled variant 655624 1.3.3.3 Fe2+ 2 atoms per native molecule 390960 1.3.3.3 Fe2+ enhanced activity by increasing concentrations up to 0.5 mM, beyond inhibitory 390978