3.6.5.4 I- - 688692 3.6.5.4 K+ - 688692 3.6.5.4 Mg2+ - 644174, 644179, 686249, 686396, 687905, 688692 3.6.5.4 Mg2+ bound 660000 3.6.5.4 Mg2+ required 756198, 757189, 757430, 757758, 757857, 758489 3.6.5.4 Mg2+ required, residues Thr64 and Ser107 are directly involved in magnesium coordination 758481 3.6.5.4 Mg2+ required, role of a magnesium ion during the GDP and GTP-bound states, overview. The binding of magnesium in the nucleotide site causes the reorientation of the beta-and gamma-phosphate groups toward the jaws of the P-loop and stabilizes the binding of the nucleotide, creating a network of hydrogen and water-bridge interactions 757514