2.1.1.214	Mg2+	required	712436, 757844	
2.1.1.214	Zinc	the enzyme is composed of at least two subunits that are associated in vivo: Trm11p, which is the catalytic subunit, and Trm112p, a putative zinc-binding protein	675961	
2.1.1.214	Zn2+	zinc might be important for Trm11 binding to Trm112, most probably by maintaining the three-dimensional structure of Trm112 zinc-binding domain, which in the other Trm112-MTase complexes is directly interacting with the MTase domains	757844