2.7.7.60	Co2+	-	692926	
2.7.7.60	Co2+	catalytically active with	393244	
2.7.7.60	divalent cation	metal-dependent enzymatic activity	692926	
2.7.7.60	Fe2+	-	692926	
2.7.7.60	Mg2+	-	393242, 393244, 661089, 705229	
2.7.7.60	Mg2+	absolute requirement of divalent metal ions like Ni2+, Mn2+, Co2+, Ca2+, Cu2+ and Zn2+ for catalytic acitvity, maximum activity with Mg2+	393242	
2.7.7.60	Mg2+	catalytically active with	393244	
2.7.7.60	Mg2+	essential for activity	393240	
2.7.7.60	Mg2+	preferred	692926	
2.7.7.60	Mg2+	preferred cation	726274	
2.7.7.60	Mg2+	required	760261, 760263, 760333, 761602, 762421	
2.7.7.60	Mg2+	the PvIspD enzyme is highly specific for Mg2+ ions	761199	
2.7.7.60	Mn2+	-	692926, 705229	
2.7.7.60	Mn2+	catalytically active with	393244	
2.7.7.60	additional information	Cu2+, Ni2+, Ca2+, Fe2+ or Zn2+ do not serve as cofactor	393244	
2.7.7.60	additional information	poor activity with Mn2+, no activity with Ca2+, Co2+, Cu2+, and Zn2+	761199	
2.7.7.60	Zn2+	-	705229