2.3.1.37	Ca2+	optimal at concentration of 50 mM, inhibition above 200 mM	486832	
2.3.1.37	Iron	regulation of erythroid-specific isoform ALAS-2 via 5'-iron responsive element, i.e. IRE	486853	
2.3.1.37	Li+	in Mg2+-containing medium: at 100 mM no effect on activity, higher concentrations are totally inhibitory	486832, 486833	
2.3.1.37	Li+	optimal at 0.5 M, not inhibitory up to 1 M	486832	
2.3.1.37	Mg2+	activates	486809	
2.3.1.37	Mg2+	inhibition of complex form, stimulation of stripped form	486837	
2.3.1.37	Mg2+	optimal at concentration of 50 mM, inhibition above 200 mM	486832	
2.3.1.37	additional information	partially purified enzyme requires high cation concentrations, equivalent to 0.3 M NaCl, for maximum activation, monovalent cations, i.e. Na+, K+, Li+, Rb+ or NH4+, in concentrations from 0.15 M to 0.30 M or divalent cations, i.e. Mg2+, Ca2+ or Mn2+, at lower concentrations of 0.03 M to 0.10 M are effective	486812	
2.3.1.37	Na+	in Mg2+-containing medium: at 100 mM no effect on activity, higher concentrations are totally inhibitory	486832, 486833	
2.3.1.37	Na+	inhibition of complex form, stimulation of stripped form	486837	
2.3.1.37	Na+	optimal at 0.5 M, not inhibitory up to 1 M	486832	
2.3.1.37	potassium ferricyanide	activates at 0.5 mM	486811