1.3.3.3	Ca2+	50% activation of anaerobic enzyme at 5 mM	390974	
1.3.3.3	Co2+	activation up to 0.1 mM, beyond inhibitory	390978	
1.3.3.3	Co2+	optimal activation only for anaerobic enzyme at 0.1 mM	390974	
1.3.3.3	Cu2+	0.06 atom per enzyme	390949	
1.3.3.3	Cu2+	1.05 atoms per enzyme	390949, 390953	
1.3.3.3	Cu2+	about 0.03 mol per mol of polypeptide for both enzyme forms	655624	
1.3.3.3	Fe2+	0.07-0.14 atom per enzyme	390949	
1.3.3.3	Fe2+	0.09-1.25 mol per mol of polypeptide for the recombinant wild-type enzyme, 0.2 mol per mol of polypeptide for the selenomethionine-labeled variant	655624	
1.3.3.3	Fe2+	2 atoms per native molecule	390960	
1.3.3.3	Fe2+	enhanced activity by increasing concentrations up to 0.5 mM, beyond inhibitory	390978	
1.3.3.3	Fe2+	optimal activation only for anaerobic enzyme at 0.1 mM	390974	
1.3.3.3	Fe2+	trace amounts	390949, 390953	
1.3.3.3	Fe3+	80% activation of anaerobic enzyme at 0.5 mM	390974	
1.3.3.3	Mg2+	50% activation of anaerobic enzyme at 5 mM	390974	
1.3.3.3	Mn2+	activation up to 0.1 mM, beyond inhibitory	390978	
1.3.3.3	Mn2+	is added to the assay at 10 mM	697204, 713258	
1.3.3.3	Mn2+	optimal activation only for anaerobic enzyme at 0.2 mM	390974	
1.3.3.3	Mn2+	required, bound to the enzyme, stimulates, restores the enzyme inactivated by metal chelators, coordinated by residues His96, His106, His145, and His175	656175	
1.3.3.3	additional information	30% activation of aerobic oxidation by divalent ions	390974	
1.3.3.3	additional information	metal ions Cu2+, Mg2+, Mn2+, Fe2+ and Zn2+ at up to 0.500 mM concentration have no effect on CPO activity	713182	
1.3.3.3	additional information	no metal content	390948, 390951, 390964