3.4.22.49 centrosome - 5813 731689, 732669, 732703 3.4.22.49 centrosome localized in centrosomes before anaphase 5813 638869 3.4.22.49 chromosome - 5694 697240, 731697 3.4.22.49 chromosome the spatial localization of separase varies with the progression of the cell cycle. In interphase cells, separase is localized in the cytoplasm, but during mitosis it accumulates in the nucleus and associates with chromosomes 5694 752903 3.4.22.49 cytoplasm Cut1 seems to be localized in the cytoplasm 5737 638856 3.4.22.49 cytoplasm in nondividing cells in healthy tissue, immunofluorescence microscopy 5737 697382 3.4.22.49 cytoplasm prodominant localisation 5737 700280 3.4.22.49 cytoplasm separase is abundantly expressed within the cytoplasm of a broad range of human tumor cell lines, including MDA-MB-231 breast carcinoma cells 5737 718433 3.4.22.49 cytoplasm the spatial localization of separase varies with the progression of the cell cycle. In interphase cells, separase is localized in the cytoplasm, but during mitosis it accumulates in the nucleus and associates with chromosomes 5737 752903 3.4.22.49 membrane - 16020 718433