1.3.99.23	endoplasmic reticulum	-	5783	672228	
1.3.99.23	endoplasmic reticulum	primarily	5783	-, 763507	
1.3.99.23	endoplasmic reticulum membrane	RetSat is predominantly in the endoplasmic reticulum (ER) where it colocalizes with the ER marker protein disulfide isomerase	5789	763769	
1.3.99.23	endoplasmic reticulum membrane	the enzyme has an N-terminal signal peptide (aa 1-18), that targets the nascent protein to the membrane of the endoplasmic reticulum, and a dinucleotide-binding domain (aa 73-118). There are several hydrophobic stretches, such as aa 567-587, that may be transmembrane domains. RetSat is predominantly in the endoplasmic reticulum (ER) where it colocalizes with the ER marker protein disulfide isomerase	5789	763769	
1.3.99.23	membrane	-	16020	672228	
1.3.99.23	membrane	associated to	16020	659418	
1.3.99.23	additional information	perinuclear staining in cells overexpressing RetSat and nuclear staining of endogenous RetSat in primary mouse hepatocytes are observed	-	763769