4.4.1.17 integral to membrane - - 94055, 94058 4.4.1.17 mitochondrial inner membrane - 5743 94056, 94057, 94058 4.4.1.17 mitochondrial inner membrane integral membrane protein, facing cytoplasmic surface 5743 94055 4.4.1.17 mitochondrial inner membrane separation of mitochondrial inner and outer membrane on a sucrose gradient 5743 665678 4.4.1.17 mitochondrial intermembrane space enzyme is transported into the intermembrane space via a direct sorting pathway, that can occur in absence of external energy sources 5758 651850 4.4.1.17 mitochondrial intermembrane space novel, non-conservative import pathway: the enzyme precursor is translocated into mitochondria using the MOM19-GIP receptor complex in the outer membrane, independent of ATP-hydrolysis and electrochemical potential as external energy source 5758 94058 4.4.1.17 mitochondrial membrane membrane-bound 31966 730827 4.4.1.17 mitochondrion - 5739 651895, 677440, 715034, 729264, 729740, 730058, 730322, 94056 4.4.1.17 mitochondrion detected by Western analysis 5739 653258 4.4.1.17 mitochondrion during apoptotic stimuli, enzyme translocates to outside the mitochondria, and binds to and suppresses the X-linked inhibitor of apoptosis protein XIAP, leading to activation of caspase-3. The N-terminus of the neuronal glutamate transporter excitatory amino-acid carrier 1 EAAC1 can bind to enzyme which interferes with the enzyme-XIAP association 5739 679489 4.4.1.17 mitochondrion integral membrane protein of inner membrane (facing cytoplasmic surface) 5739 94055 4.4.1.17 mitochondrion intermembrane space 5739 94057, 94058 4.4.1.17 mitochondrion mitoplast 5739 94055 4.4.1.17 mitochondrion novel, non-conservative import pathway: the enzyme precursor is translocated into mitochondria using the MOM19-GIP receptor complex in the outer membrane, independent of ATP-hydrolysis and electrochemical potential as external energy source 5739 94058 4.4.1.17 soluble - - 94057