3.6.5.4 chloroplast - 9507 668340, 670542, 686752, 688395, 696602, 698898, 701227, 757189 3.6.5.4 chloroplast chloroplast SRP 9507 718911 3.6.5.4 chloroplast chloroplasts contain a signal recognition particle that lacks RNA but contains a conserved 54000 Da GTPase and a novel 43000 Da subunit 9507 669412 3.6.5.4 chloroplast the chloroplast signal recognition particle (cpSRP) is a heterodimer composed of an evolutionarily conserved 54-kDa GTPase (cpSRP54) and a unique 43-kDa subunit (cpSRP43) responsible for delivering light harvesting chlorophyll binding protein to the thylakoid membrane 9507 756198 3.6.5.4 cytoplasm - 5737 684117, 686249 3.6.5.4 cytosol cytosolic SRP 5829 718911 3.6.5.4 cytosol SRP subunit SRP54 5829 644166, 644167, 644168 3.6.5.4 cytosol the SRP targets the ribosome-nascent chain complexes to the inner membrane by interacting with the SRP receptor 5829 690025 3.6.5.4 endoplasmic reticulum - 5783 696594 3.6.5.4 endoplasmic reticulum SRP receptor alpha and beta subunits 5783 644166, 644167, 644169, 644171, 644180 3.6.5.4 endoplasmic reticulum SRP receptor alpha subunit 5783 644163, 644164, 644173, 644174 3.6.5.4 endoplasmic reticulum membrane - 5789 -, 757758, 757857, 758481 3.6.5.4 endoplasmic reticulum membrane peripheral membrane SRalpha subunit, the transmembrane SRbeta subunit is anchoring SRalpha on the endoplasmic reticulum membrane 5789 757430 3.6.5.4 inner membrane the SRP targets the ribosome-nascent chain complexes to the inner membrane by interacting with the SRP receptor - 690025 3.6.5.4 membrane - 16020 684117, 686249, 686752, 687902, 758489 3.6.5.4 membrane microsomal membrane 16020 687905 3.6.5.4 membrane peripheral membrane protein subunit SRalpha, which is anchored to the membrane by the 30 kDa subunit SRbeta, that has a single N-terminal transmembrane domain and short luminal domain 16020 757758 3.6.5.4 membrane peripheral membrane SRalpha subunit, the transmembrane SRbeta subunit is anchoring SRalpha on the endoplasmic reticulum membrane 16020 757430 3.6.5.4 membrane SRbeta is an integral membrane component of the signal recognition particle (SRP) receptor 16020 -, 758481 3.6.5.4 additional information the domain of SRalpha that binds SRbeta does so by binding directly to the nucleotide bound form of the GTPase domain of SRbeta. Additional level of regulation of SRP receptor function based on regulated dissociation of the receptor subunits - 757430 3.6.5.4 nucleolus - 5730 669585 3.6.5.4 ribosome - 5840 -, 700091, 701200 3.6.5.4 ribosome the SRbeta-ribosome interaction relies on SRalpha, when SRbeta is in the GTP-bound state 5840 -, 758481 3.6.5.4 ribosome the SRP targets the ribosome-nascent chain complexes to the inner membrane by interacting with the SRP receptor 5840 690025