3.4.21.20 azurophil granule - 42582 36500, 664269, 665169, 665913, 709987 3.4.21.20 cell surface - 9986 718143, 753787 3.4.21.20 cell surface active enzyme 9986 683193 3.4.21.20 cell surface expression at high levels on the surface of activated human neutrophils in catalytically active but inhibitor-resistant form 9986 683644 3.4.21.20 cytoplasmic vesicle - 31410 653667 3.4.21.20 endocytic vesicle - 30139 709987 3.4.21.20 extracellular - - 653069, 653984 3.4.21.20 extracellular active enzyme - 683193 3.4.21.20 extracellular enzyme is released on degranulation of neutrophils - 651583 3.4.21.20 intracellular - 5622 709983 3.4.21.20 lysosome - 5764 36500, 36501, 665912, 709353 3.4.21.20 lysosome derived from primary murine microglia 5764 683531 3.4.21.20 lysosome microglia-derived 5764 683531 3.4.21.20 membrane - 16020 36519, 36523, 718414 3.4.21.20 nucleus apoptotic NB4 cells 5634 653667 3.4.21.20 plasma membrane mechanism by which the enzyme binds to activated human neutrophil plasma membranes, a functional active site is not required for binding, overview, inhibition of binding by 1. trypsin, chondroitinase ABC, and heparitinases, but not other glycanases, and by 2. purified chondroitin sulfates, heparan sulfate, and other sulfated molecules, but not by non-sulfated glycans, binding kinetics, overview 5886 683644