2.1.1.204 cytoplasm - 5737 708586 2.1.1.204 cytoplasm Dnmt2 is both a cytoplasmic and a nuclear protein 5737 710349 2.1.1.204 cytoplasm granular cytoplasmic distribution with minor signals in the nucleus. Large structures appear in the cytoplasm and in the nucleus upon heat stress 5737 708588 2.1.1.204 cytoplasm human DNMT2 protein (hDNMT2) is primarily localized to the cytoplasm of transfected mouse 3T3 fibroblasts 5737 710560 2.1.1.204 additional information the major function of the N-terminal domain is to determine subcellular localization of the enzyme - 735727 2.1.1.204 nucleus - 5634 735864 2.1.1.204 nucleus Dnmt2 is both a cytoplasmic and a nuclear protein. A significant amount of Dnmt2 is bound to the nuclear matrix. Dnmt2-EGFP(enhanced-green-fluorescent-protein) enters prophase nuclei and shows a spindle-like localization pattern during mitotic divisions. This localization is microtubule dependent. Dnmt2 can access DNA during mitotic cell divisions 5634 710349