2.1.1.137 arsenite the enzyme activity is completely inhibited by elevated concentrations of the substrate arsenite (0.2 mM) 397 2.1.1.137 dimethylselenoxide weak activator of recombinant As(III)-methyltransferase, weak inhibitor of arsenite methylation in hepatocytes 23300 2.1.1.137 glutathione addition of 20 mM GSH sharply inhibits methylation 44 2.1.1.137 GSH suppression of formation of trimethylarsine oxide, stimulatory effect on the rate of methylarsonate and dimethylarsinate production from arsenite is concentration-dependent 142 2.1.1.137 GSH addition of GSH stimulates the overall rate for As methylation, but inhibits formation of trimethylarsenite 142 2.1.1.137 HgCl2 - 110 2.1.1.137 methylselenic acid - 34890 2.1.1.137 selenate more than 1 mM selenate necessary for 50% inhibition 2162 2.1.1.137 Selenite 50% inhibition with 0.0126 mM selinite 1937 2.1.1.137 Selenite addition of selenite at 1:10 molar ratio with arsenite in the reaction mixture completely abolishes the arsenic methylation 1937