1.5.5.2	additional information	no enzyme inhibibtion by atpenin A5, an inhibitor of Complex II	2	
1.5.5.2	pyruvate	-	31	
1.5.5.2	acetate	competitive	47	
1.5.5.2	succinate	uncompetitive inhibitor, in the presence of low levels of proline in vivo, higher levels of succinate can act to inhibit PRODH/POX activity and reactive oxygena species generation. The affinity of succinate is for the enzyme-substrate complex of PRODH/POX and proline rather than for the enzyme binding site for proline. Succinate protects electron transport chain component proteins from PRODH/POX reactive oxygen species-mediated downregulation with almost the same efficacy as 3,4-dehydro-L-proline and N-acetyl-L-cysteine	58	
1.5.5.2	cyanide	only membrane-associated enzyme, not soluble enzyme	118	
1.5.5.2	KCN	very strong inhibition	161	
1.5.5.2	L-proline	substrate inhibition at high L-proline concentrations; substrate inhibition at high L-proline concentrations	243	
1.5.5.2	L-proline	substrate inhibition at high L-proline concentrations	243	
1.5.5.2	L-lactate	-	403	
1.5.5.2	L-lactate	competitive	403