3.6.1.8 15-desoxybludein 0.065 mg/ml, 11% inhibition 132697 3.6.1.8 AMP slight inhibition 30 3.6.1.8 Caffeine 25% inhibition at 3 mM 882 3.6.1.8 cAMP 20% inhibition at 3 mM 268 3.6.1.8 eremantolide C 0.065 mg/ml, 17% inhibition 132698 3.6.1.8 glaucolide A 0.065 mg/ml, 11% inhibition 132692 3.6.1.8 glaucolide B 0.065 mg/ml, 16% inhibition 132693 3.6.1.8 GMP competitive inhibition with Ki: 0.001 mM 162 3.6.1.8 goyazensolide 0.065 mg/ml, 10% inhibition 132695 3.6.1.8 isogoyazensolide 0.065 mg/ml, 11% inhibition 132696 3.6.1.8 licnofolide 0.065 mg/ml, 22% inhibition 132694 3.6.1.8 licoflavone B isolated from Glycyrrhiza inflata, possesses high in vitro schistosomicidal activity against adult worms of Schistosoma mansoni. Licoflavone B causes massive damage in the worm's tegument and inhibits egg laying, without affecting mammalian Vero cells. The tegument of Schistosoma mansoni is crucial for the parasite survival and its host immune defense. Licoflavone B is highly effective in inhibiting Schistosoma mansoni ATP diphosphohydrolase, docking studies with licoflavone B and SmATPase 1 revealing a spontaneous process. The docking study predicts different interactions between licoflavone B and ATPDase 1, corroborating with the in vitro inhibitory activity. Licoflavone B also shows inhibitory activity against ATPase in Schistosoma mansoni 243960 3.6.1.8 additional information no inhibition by 0.065 mg/ml 15-desoxygoyazensolide 2 3.6.1.8 additional information in vitro schistosomicidal activity of the crude extract of Glycyrrhiza inflata roots containing echinatin, licoflavone A and licoflavone B 2 3.6.1.8 phosphatidylserine - 430 3.6.1.8 thapsigargicin 0.065 mg/ml, 57% inhibition 132699 3.6.1.8 thapsigargin inhibits ATP hydrolysis, 70% inhibition at 0.065 mg/ml, mixed type inhibition, little or not affected by changes in free Ca2+ or Mg2+ concentrations, hydrolysis of ADP is not inhibited 2240 3.6.1.8 UDPGlc very weak 107457