3.6.1.28	([2-[3-(4-Amino-2-methyl-pyrimidin-5-ylmethyl)-4-methyl-thiazol-5-yl]-ethoxy]-phosphonomethyl-phosphinoylmethyl)-phosphonic acid	-	33677	
3.6.1.28	1-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-hydroxyethyl)-2-methylpyridinium	soluble enzyme: 50% inhibition at 2 mM. Membrane-bound enzyme: no inhibition up to 5 mM	44751	
3.6.1.28	4,4'-diisothiocyanostilbene-2,2'-disulfonic acid	1.0 mM, 62% inhibition of membrane-associated enzyme	12359	
3.6.1.28	4-acetamide-4'-isothiocyanostilbene-2,2'-disulfonic acid	1.0 mM, 36% inhibition of membrane-associated enzyme	104956	
3.6.1.28	5,5'-dithiobis-2-nitrobenzoic acid	-	5368	
3.6.1.28	acetone	-	333	
3.6.1.28	ADP	0.001-1 mM, strong inhibition	13	
3.6.1.28	ADP	-	13	
3.6.1.28	ADP	1 mM, strongly inhibits membrane-associated enzyme, soluble enzyme is unaffected	13	
3.6.1.28	ApCp	-	16062	
3.6.1.28	AppCp	-	105463	
3.6.1.28	ATP	-	4	
3.6.1.28	ATP	1 mM, strongly inhibits membrane-associated enzyme, soluble enzyme is unaffected	4	
3.6.1.28	ATP	soluble enzyme: no inhibition up to 2 mM, membrane-bound enzyme: 50% inhibition at 5 mM	4	
3.6.1.28	ATP	very poor inhibitor	4	
3.6.1.28	Br-	soluble enzyme	332	
3.6.1.28	Br-	inhibitory at 150 mM	332	
3.6.1.28	Ca2+	0.2 mM CaCl2, 50% inhibition	15	
3.6.1.28	Ca2+	-	15	
3.6.1.28	Ca2+	physiological concentrations markedly inhibit soluble TTPase	15	
3.6.1.28	Ca2+	0.1-1.0 mM, in presence of Mg2+, soluble enzymem	15	
3.6.1.28	Ca2+	soluble enzyme: 50% inhibition at 5 mM, membrane-bound enzyme: 20% inhibition at 5 mM	15	
3.6.1.28	Ca2+	inhibits by competition with Mg2+	15	
3.6.1.28	Ca2+	Ca2+ inhibits hThTPase activity through competition with Mg2+	15	
3.6.1.28	chlorpromazine	1.0 mM, 61% loss of activity	727	
3.6.1.28	chlorpromazine	microsomal and soluble enzyme	727	
3.6.1.28	chlorpromazine	microsomal and soluble enzyme; no inhibition in presence of Ca2+	727	
3.6.1.28	Cl-	soluble enzyme	141	
3.6.1.28	Cl-	inhibitory at 150 mM	141	
3.6.1.28	Colchicine	1.0 mM, 16% inhibition	3334	
3.6.1.28	deoxycholate	-	441	
3.6.1.28	deoxycholate	0.02% w/v	441	
3.6.1.28	desipramine	-	4002	
3.6.1.28	desipramine	microsomal and soluble enzyme	4002	
3.6.1.28	F-	5 mM, 55% inhibition	174	
3.6.1.28	I-	soluble enzyme	507	
3.6.1.28	I-	inhibitory at 150 mM	507	
3.6.1.28	imipramine	microsomal and soluble enzyme	1618	
3.6.1.28	Mg2+	excess of Mg2+ over thiamine triphosphate inhibits	6	
3.6.1.28	N-dodecyl-N,N-dimethyl-3-amino-1-propanesulfonate	-	106683	
3.6.1.28	NO3-	soluble enzyme	673	
3.6.1.28	NO3-	inhibition at pH 6.0. At pH 7.6 slight but consistent activation at 50 mM NO3-, higher concentrations are inhibitory	673	
3.6.1.28	NO3-	inhibitory at 150 mM	673	
3.6.1.28	PCMB	-	78	
3.6.1.28	SCN-	soluble enzyme	1032	
3.6.1.28	SCN-	inhibitory at 150 mM	1032	
3.6.1.28	SDS	IC50: about 0.3% W/v. The inhibition is partially reversible, probably due to correct refolding of the denatured enzyme	124	
3.6.1.28	SO42-	-	245	
3.6.1.28	thiamine beta,gamma-methylene phosphonate	-	105554	
3.6.1.28	thiamine diphosphate	0.75 mM, 55% inhibition	91	
3.6.1.28	thiamine diphosphate	soluble enzyme, at levels of substrate 2 to 3 times Km, no inhibition of membrane-associated enzyme	91	
3.6.1.28	thiamine phosphate	0.75 mM, 12% inhibition	4570	
3.6.1.28	thiamine triphosphate	substrate inhibition	2224	
3.6.1.28	thiamine triphosphate	-	2224	
3.6.1.28	vanadate	1.0 mM, 27% inhibition of membrane-associated enzyme	233	
3.6.1.28	Zn2+	0.5 mM, 59% inhibition of membrane-associated enzyme	14	
3.6.1.28	Zn2+	inhibits at micromolar concentrations at pH 8.0, IC50: about 0.015-0.02 mM. Activates at pH 6.0	14	
3.6.1.28	Zn2+	pH 8.5, IC50: 0.007 mM	14