3.4.23.12 4-(2-aminoethyl)benzenesulfonyl fluoride about 70% residual activity at 0.1 mM 4308 3.4.23.12 CoSO4 - 3452 3.4.23.12 CuCl2 - 347 3.4.23.12 cupric ions strong inhibition of nepenthesin I and II by diazoacetyl-DL-norleucine in presence of cupric ions, no inactivation in absence of cupric ions 118050 3.4.23.12 diazoacetyl-DL-norleucine strong inhibition of nepenthesin I and II in presence of cupric ions, no inactivation in absence of cupric ions 21129 3.4.23.12 Diazoacetyl-DL-norleucine methyl ester i.e. DAN 1233 3.4.23.12 dithiothreitol isoforms nethepsin I, IIa and IIb are completely inactivated in the presence of 40-70 mM dithiothreitol 45 3.4.23.12 DL-Norleucine methyl ester - 29970 3.4.23.12 DMSO about 65% residual activity at 0.1 mM 896 3.4.23.12 E-64 about 97% residual activity at 0.02 mM 559 3.4.23.12 guanidine hydrochloride isoform NepII shows about 85% residual activity at 4 M, about 50% residual activity at 5 M, and is completely inhibited at 6 M guanidine hydrochloride; isoform NepI shows about 50% residual activity at 1 M and is completely inhibited at 4 M guanidine hydrochloride 1048 3.4.23.12 HgCl2 - 110 3.4.23.12 additional information isoform NepII is not inhibited by urea 2 3.4.23.12 N-(diazoacetyl)-N-(2,4-dinitrophenyl)ethylenediamine - 132563 3.4.23.12 pepstatin - 396 3.4.23.12 pepstatin A 0.1 mM, complete inhibition of nepenthesin I and II 309 3.4.23.12 pepstatin A - 309 3.4.23.12 pepstatin A almost complete inhibition at 0.1 mM 309 3.4.23.12 Phenanthroline about 65% residual activity at 0.1 mM 4856 3.4.23.12 Urea isoform NepI shows about 85% residual activity at 4 M and is completely inhibited at 6 M urea 116