3.4.22.41 1,10-phenanthroline 15.28% inhibition at 0.1 mM 62 3.4.22.41 antipain complete inhibition at 0.1 mM 520 3.4.22.41 Aprotinin 36.94% inhibition at 0.1 mM 405 3.4.22.41 Chloroquine - 1439 3.4.22.41 chymostatin 35.42% inhibition at 0.1 mM 511 3.4.22.41 Co2+ 6.85% residual activity at 5 mM 23 3.4.22.41 Cu2+ 11.6% residual activity at 5 mM 19 3.4.22.41 cystatin B - 9663 3.4.22.41 E-64 56.3% inhibition at 0.1 mM 559 3.4.22.41 E-64 effective inhibition 559 3.4.22.41 E-64 - 559 3.4.22.41 EDTA 6.52% inhibition at 0.1 mM 21 3.4.22.41 EGTA 4.72% inhibition at 0.1 mM 173 3.4.22.41 Hg2+ 0.81% residual activity at 5 mM 33 3.4.22.41 JPM565 radioactive-labeling by 125I, irrevrsible inhibitor of papin-type cathepsins, active site labeling 132532 3.4.22.41 leupeptin complete inhibition at 0.1 mM 217 3.4.22.41 additional information downregulation of cathepsin F mRNA by E-64d; treatment with retinol/palmitic acid increases mRNA-level of cystatin B coupled with decrease in cathepsin F activity; treatment with retinol/palmitic acid increases mRNA-level of cystatin C coupled with decrease in cathepsin F activity 2 3.4.22.41 additional information not inhibited by pepstatin A 2 3.4.22.41 additional information the prodomain effectively inhibits the enzyme in which the ERFNAQ motif plays a critical role in the inhibition, but the GTFD motif is also required for complete inhibition 2 3.4.22.41 morpholine urea-Leu-homophenylalaninevinyl sulfone-phenyl potent and irreversible inhibitor of cysteine proteases 47985 3.4.22.41 morpholine urea-Leu-homophenylalaninevinyl sulfone-phenyl - 47985 3.4.22.41 NEM 44.59% inhibition at 0.1 mM 89 3.4.22.41 phenylmethylsufonyl fluoride 13.22% inhibition at 0.1 mM 160124 3.4.22.41 SDS complete inhibition at 0.05% (w/v) 124 3.4.22.41 trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane i.e. E-64 1306 3.4.22.41 trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane - 1306 3.4.22.41 Z-VAD(OMe)-fluoromethylketone - 201886 3.4.22.41 Zn2+ 5.94% residual activity at 1 mM 14