3.4.22.26 (D)-Phe-Pro-(D,L)-(4'-guanidino)-Phe-trifluoromethyl ketone - 97508 3.4.22.26 (D)-Phe-Pro-(D,L)-Lys-trifluoromethyl ketone weak 90300 3.4.22.26 (D)-Phe-Pro-Arg-chloromethyl ketone - 90301 3.4.22.26 (NH4)2SO4 76% inhibition at about 40 mM 399 3.4.22.26 2-Vinylpyridine - 91201 3.4.22.26 alpha1-Aantichymotrypsin weak 2590 3.4.22.26 alpha2-Macroglobulin weak 1068 3.4.22.26 antiCP polyclonal antibody - 151609 3.4.22.26 antiFVIIa polyclonal antibody - 151610 3.4.22.26 antipain enhanced in reduced environment 520 3.4.22.26 antipain - 520 3.4.22.26 benzamidine strong inhibition 579 3.4.22.26 benzoxycarbonyl-Lys-CHN2 - 92540 3.4.22.26 CaCl2 91% inhibition at about 40 mM 218 3.4.22.26 Cu2+ inactivation 19 3.4.22.26 Cu2+ 1 mM: 46% decrease of activity (not statistically significant) 19 3.4.22.26 diisopropylfluorophosphate strong 299 3.4.22.26 E-64 - 559 3.4.22.26 E64 - 1457 3.4.22.26 E64 specific inhibition 1457 3.4.22.26 EDTA low inhibition 21 3.4.22.26 Fe2+ in the presence of Ca2+, complete inactivation at 1 mM Fe2+ and above 25 3.4.22.26 Fe2+ inactivation 25 3.4.22.26 Hg2+ 0.1 mM: 85.5% decrease of activity 33 3.4.22.26 HgCl2 0.1 mM 110 3.4.22.26 HgCl2 Hg2+ 110 3.4.22.26 HgCl2 strong, less effective in reduced environment 110 3.4.22.26 HgCl2 complete inhibition at about 40 mM 110 3.4.22.26 iodoacetamide 1 mM 67 3.4.22.26 iodoacetamide - 67 3.4.22.26 iodoacetamide strong, still enhanced in reduced environment 67 3.4.22.26 leupeptin - 217 3.4.22.26 leupeptin enhanced in reduced environment 217 3.4.22.26 Mercuric chloride - 5577 3.4.22.26 MgCl2 81% inhibition at about 40 mM 196 3.4.22.26 MgSO4 68% inhibition at about 40 mM 1205 3.4.22.26 Mn2+ above 1 mM, activates below 1 mM 11 3.4.22.26 additional information no inhibition by cystamine, benzoxycarbonyl-Val-Phe 2 3.4.22.26 additional information cystatin, alpha1-antiprotease, antithrombin III 2 3.4.22.26 additional information no inhibition by alpha2-macroglobulin, alpha1-antiprotease, antithrombin III/heparin, cystatin, cysteamine, alpha1-anichymotrypsin, the effectiveness of most of the inhibitors increase in presence of reducing agents 2 3.4.22.26 additional information inhibition by specific anti-CP antibodies 2 3.4.22.26 additional information no or poor inhibition by iodoacetamide and E-64 2 3.4.22.26 N-benzyloxycarbonyl-Phe-Ala-CHN2 - 92541 3.4.22.26 NaCl 12-21% inhibition, respectively 42 3.4.22.26 p-chloromercuric benzoate - 33796 3.4.22.26 pepstatin A low inhibition 309 3.4.22.26 Peptidyl chloromethanes - 30942 3.4.22.26 Peptidyl diazomethanes - 16160 3.4.22.26 Peptidyl diazomethyl ketones - 30867 3.4.22.26 Peptidyl dimethylsulfonium salts - 46862 3.4.22.26 Peptidyl sulfonium salts - 99576 3.4.22.26 phenylmethylsulfonyl fluoride - 257 3.4.22.26 Phenylmethylsulfonylfluoride strong inhibition 1148 3.4.22.26 PMSF - 248 3.4.22.26 Sn2+ inactivation 413 3.4.22.26 trans-epoxysuccinyl-L-leucyl-amido(4-guanidino)butane i.e. E-64, thiol protease inhibitor, factor X protects 8202 3.4.22.26 trans-epoxysuccinyl-L-leucyl-amido(4-guanidino)butane enhanced in reduced environment 8202 3.4.22.26 trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane i.e. E-64, reversible, competitive 1306 3.4.22.26 trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane ie.e. E-64, reversible, competitive 1306 3.4.22.26 trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane ie.e. E-64 1306 3.4.22.26 Zn2+ in the presence of Ca2+, complete inactivation at 1 mM Zn2+ and above 14 3.4.22.26 Zn2+ inactivation 14