3.4.22.10	(S)-1-azido-2-tosylamino-hexane	moderate inhibitor of IdeS	159997	
3.4.22.10	(S)-1-azido-3-methyl-2-tosylamino-butane	moderate inhibitor of IdeS	159998	
3.4.22.10	(S)-1-azido-3-phenyl-2-tosylamino-propane	moderate inhibitor of IdeS	159996	
3.4.22.10	(S)-3-tosylamino-1-heptanal	strong inhibitory activity	159992	
3.4.22.10	(S)-3-tosylamino-heptane-1-nitrile	the compound shows some inhibition of IdeS	159995	
3.4.22.10	(S)-4-methyl-3-tosylamino-1-pentanal	strong inhibitory activity	159993	
3.4.22.10	(S)-4-phenyl-3-tosylamino-1-butanal	strong inhibitory activity	159991	
3.4.22.10	(S)-7-tert-butoxycarbonylamino-3-tosylamino-1-heptanal	strong inhibitory activity	159994	
3.4.22.10	1,3-Dibromoacetone	rapid and complete loss of activity	19850	
3.4.22.10	2,4-dinitrofluorobenzene	-	7981	
3.4.22.10	acetonitrile	mixed type	981	
3.4.22.10	acetyl-Ala-Gln-Ile-(S)-2,6-diaminohexanal	-	206267	
3.4.22.10	benzyloxycarbonyl-Ala-Ala-CHN2	-	100204	
3.4.22.10	benzyloxycarbonyl-Ala-Ala-Pro-CHN2	-	100206	
3.4.22.10	benzyloxycarbonyl-Ala-Phe-Ala-CHN2	-	100217	
3.4.22.10	benzyloxycarbonyl-Asn-Val-Gly-CHN2	inhibition of protease activity, no influence on the superantigenic properties of the enzyme	100223	
3.4.22.10	Benzyloxycarbonyl-Gly-Phe	competitive against benzyloxycarbonyl-Phe-Tyr	3618	
3.4.22.10	benzyloxycarbonyl-Leu-Val-Gly-CHN2	inhibits kininogen degradation	100267	
3.4.22.10	Benzyloxycarbonyl-Phe-Ala-CHN2	-	8055	
3.4.22.10	benzyloxycarbonyl-Phe-Gly-CHN2	-	100279	
3.4.22.10	benzyloxycarbonyl-Phe-Gly-Phe-CHN2	-	100280	
3.4.22.10	Cu2+	Cu2+ inhibits the proteolytic activity of mature SpeB	19	
3.4.22.10	dimethyl sulfoxide	competitive	1217	
3.4.22.10	E-64	0.028 mM	559	
3.4.22.10	E-64	i.e. L-trans-epoxysuccinyl-leucylamido(4-guanidino)butane, irreversible inhibition	559	
3.4.22.10	E64	i.e. trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane	1457	
3.4.22.10	Gly-Phe-CHN2	-	100615	
3.4.22.10	HgCl2	prevents the conversion to the mature 28 kDa form	110	
3.4.22.10	HgCl2	-	110	
3.4.22.10	iodoacetamide	-	67	
3.4.22.10	iodoacetate	irreversible inhibitor	93	
3.4.22.10	iodoacetic acid	-	213	
3.4.22.10	L-trans-epoxysuccinyl-leucylamido(4-guanidino)butane	-	151599	
3.4.22.10	methyliodine	-	100929	
3.4.22.10	additional information	IdeS is not inhibited by E-64, (S)-3-phenyl-2-tosylamino-1-propanol, (S)-2-tosylamino-1-hexanol, (S)-3-methyl-2-tosylamino-1-butanol, (S)-6-tert-butoxycarbonylamino-2-tosylamino-1-hexanol, (S)-6-amino-2-tosylamino-1-hexanol trifluoroacetic acid, (S)-3-phenyl-2-tosylamino-propyl-1-toluenesulfonate, (S)-2-tosylamino-hexyl-1-toluenesulfonate, (S)-3-methyl-2-tosylamino-butyl-1-toluenesulfonate, and (S)-6-tert-butoxycarbonylamino-2-tosylamino-hexyl-1-toluenesulfonate	2	
3.4.22.10	additional information	antibodies produced against the r28-kDa truncated form of the C192 mutant enzyme effectively inhibit digestion of casein or fibrinogen by cysteine protease wheras antibodies generated against the r40-kDA form of the mutant have no significant effect on proteolysis	2	
3.4.22.10	N-(N-(L-3-trans-carboxyoxirane-2-carbonyl)-L-leucyl)-agmatine	-	206266	
3.4.22.10	N-[N-(L-3-transcarboxyirane-2-carbonyl)-L-leucyl]agmatine	-	139047	
3.4.22.10	Nalpha-benzyloxycarbonyl-Phe-Phe	strong inhibition of hydrolysis of Nalpha-benzyloxycarbonyl-Phe-Tyr	47409	
3.4.22.10	NEM	-	89	
3.4.22.10	Sodium tetrathionate	-	6592	
3.4.22.10	Spe B pro-peptide	specific inhibition of the mature enzyme, secondary structure and SpeB binding analysis, inhibition modeling and mechanism, overview	132491	
3.4.22.10	Spi	specific enzyme pro-peptide analogue inhibitor, purification from Streptococcus pyogenes, secondary structure and SpeB binding analysis, inhibition modeling and mechanism, overview	132490	
3.4.22.10	sulfite	-	92	
3.4.22.10	tosyl-L-lysine chloromethyl ketone	irreversible inhibitor	6601	
3.4.22.10	tosyl-L-phenylalanine chloromethyl ketone	irreversible inhibitor	9281	
3.4.22.10	Tosyl-norleucine-Phe	competitive against benzyloxycarbonyl-norleucine-Phe	95212	
3.4.22.10	trans-epoxysuccinyl-L-leucylamido(4-guanidino)butane	-	26691	
3.4.22.10	trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane	i.e. E64	1306	
3.4.22.10	trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane	i.e. E64, inhibits the capillary permeability increasing effect of the enzyme	1306	
3.4.22.10	trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane	i.e. E64, complete inhibition at 0.016 mM	1306	
3.4.22.10	trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane	-	1306	
3.4.22.10	Z-LVG-CHN2	irreversible inhibitor	159990	
3.4.22.10	Zn2+	Zinc inhibits the proteolytic activity of mature SpeB	14