1.13.11.70 (2E)-3-(3,4-dimethoxyphenyl)-N-hydroxyprop-2-enamide over 95% inhibition at 0.1 mM 219585 1.13.11.70 (2E)-N-benzyl-N-hydroxy-3,7-dimethylocta-2,6-dienamide 52% inhibition at 0.1 mM 222756 1.13.11.70 (2E)-N-hydroxy-3-(4-methoxyphenyl)prop-2-enamide over 95% inhibition at 0.1 mM 219587 1.13.11.70 (2E,4E)-N-benzyl-N-hydroxy-5,9-dimethyldeca-2,4,8-trienamide 47% inhibition at 0.1 mM 222757 1.13.11.70 (2E,4E)-N-hydroxy-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)penta-2,4-dienamide over 95% inhibition at 0.1 mM 222758 1.13.11.70 2-(2H-1,3-benzodioxol-5-yl)-N-[(4-fluorophenyl)methyl]-N-hydroxyacetamide over 95% inhibition at 0.1 mM 219583 1.13.11.70 2-(3,4-dimethoxyphenyl)-N-[(4-fluorophenyl)methyl]-N-hydroxyacetamide over 95% inhibition at 0.1 mM 223038 1.13.11.70 3-(3,4-dimethoxyphenyl)-N-hydroxy-N-octylpropanamide over 95% inhibition at 0.1 mM 220261 1.13.11.70 3-(3,4-dimethoxyphenyl)-N-hydroxypropanamide 78% inhibition at 0.1 mM 219586 1.13.11.70 3-amino-N-benzyl-N-hydroxybenzamide over 95% inhibition at 0.1 mM 223250 1.13.11.70 abamine over 95% inhibition at 0.1 mM 151016 1.13.11.70 additional information no evidence for feedback regulation 2 1.13.11.70 additional information AtCCD8 is inhibited in a time-dependent fashion by hydroxamic acids N-[(4-fluorophenyl)methyl]-N-hydroxy-2-(4-hydroxyphenyl)acetamide, N-[(4-fluorophenyl)methyl]-N-hydroxy-2-(4-methoxyphenyl)acetamide, N-benzyl-2-(3,4-dimethoxyphenyl)-N-hydroxyacetamide and 2-(3,4-dimethoxyphenyl)-N-[(4-fluorophenyl)methyl]-N-hydroxyacetamide with over 95% inhibition at 0.10 mM, hydroxamic acids acids N-[(4-fluorophenyl)methyl]-N-hydroxy-2-(4-hydroxyphenyl)acetamide, N-[(4-fluorophenyl)methyl]-N-hydroxy-2-(4-methoxyphenyl)acetamide, N-benzyl-2-(3,4-dimethoxyphenyl)-N-hydroxyacetamide and 2-(3,4-dimethoxyphenyl)-N-[(4-fluorophenyl)methyl]-N-hydroxyacetamide cause a shoot branching phenotype in Arabidopsis thaliana. Selective inhibition of CCD8 is observed using hydroxamic acids N-hydroxy-3-(4-methoxyphenyl)propanamide and N-[(4-fluorophenyl)methyl]-N-hydroxy-3-(4-methoxyphenyl)propanamide. No inhibition by N1-[(4-fluorophenyl)methyl]-N1-hydroxy-N4-[(4-methoxyphenyl)methyl]butanediamide 2 1.13.11.70 N-benzyl-2-(3,4-dimethoxyphenyl)-N-hydroxyacetamide over 95% inhibition at 0.1 mM 223973 1.13.11.70 N-benzyl-3-chloro-N-hydroxybenzamide over 95% inhibition at 0.1 mM 223977 1.13.11.70 N-benzyl-N-hydroxy-2-(4-hydroxyphenyl)acetamide over 95% inhibition at 0.1 mM 223982 1.13.11.70 N-benzyl-N-hydroxy-3,4-dimethoxybenzamide over 95% inhibition at 0.1 mM 223983 1.13.11.70 N-benzyl-N-hydroxy-3-(4-methoxyphenyl)propanamide over 95% inhibition at 0.1 mM 223984 1.13.11.70 N-benzyl-N-hydroxy-4-methoxybenzamide over 95% inhibition at 0.1 mM 223985 1.13.11.70 N-hydroxy-3-(4-methoxyphenyl)-N-octylpropanamide over 95% inhibition at 0.1 mM 223991 1.13.11.70 N-hydroxy-3-(4-methoxyphenyl)propanamide over 95% inhibition at 0.1 mM 219588 1.13.11.70 N-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-N-hydroxy-2-(4-methoxyphenyl)acetamide 70% inhibition at 0.1 mM 224000 1.13.11.70 N-[(4-fluorophenyl)methyl]-N-hydroxy-2-(4-hydroxyphenyl)acetamide over 95% inhibition at 0.1 mM 224018 1.13.11.70 N-[(4-fluorophenyl)methyl]-N-hydroxy-2-(4-methoxyphenyl)acetamide over 95% inhibition at 0.1 mM 224019 1.13.11.70 N-[(4-fluorophenyl)methyl]-N-hydroxy-3,4-dimethoxybenzamide over 95% inhibition at 0.1 mM 224020 1.13.11.70 N-[(4-fluorophenyl)methyl]-N-hydroxy-3-(4-methoxyphenyl)propanamide over 95% inhibition at 0.1 mM 224021 1.13.11.70 N-[(4-fluorophenyl)methyl]-N-hydroxy-4-methoxybenzamide over 95% inhibition at 0.1 mM 224022 1.13.11.70 N1-[(4-fluorophenyl)methyl]-N1-hydroxy-N4-[(4-methoxyphenyl)methyl]butanediamide - 224112 1.13.11.70 sodium 3-[hydroxy[(4-methoxyphenyl)acetyl]amino]propanoate 47% inhibition at 0.1 mM 224165 1.13.11.70 sodium 3-[hydroxy[(naphthalen-2-yl)acetyl]amino]propanoate 92% inhibition at 0.1 mM 224166