2.1.1.137	coenzyme M	-	733740	
2.1.1.137	dimethylselenoxide	weak activator of recombinant As(III)-methyltransferase, weak inhibitor of arsenite methylation in hepatocytes	658442	
2.1.1.137	dithiothreitol	-	485152, 733740	
2.1.1.137	dithiothreitol	weak activation	485148	
2.1.1.137	glutathione	-	485152	
2.1.1.137	glutathione	1 mM GSH decreases Km and increases Vmax estimates for arsenite and methylarsonous acid	721075	
2.1.1.137	glutathione	a 4fold increase in glutathione concentration, 2 to 8 mM, leads to a 2fold increase in enzyme activity, reducing environment is required for enzyme activity	485148	
2.1.1.137	glutathione	ArsM is able to methylate As(III) in the presence of Cys without glutathione. In contrast, ArsM is not able to methylate As(III) in the presence of tris(2-carboxyethyl)phosphine without GSH	757684	
2.1.1.137	glutathione	As(III) SAM methyltransferase conducts three successive rounds of oxidative methylation, with the glutathione conjugates serving as metalloid donors to the enzyme	718946	
2.1.1.137	glutathione	GSH should combine with the enzyme after the methylation to reduce the disulfide bond formed during the catalytic cycle to resume the active form of the enzyme	719007	
2.1.1.137	GSH	-	733740	
2.1.1.137	GSH	addition of GSH stimulates the overall rate for As methylation, but inhibits formation of trimethylarsenite	673463	
2.1.1.137	GSH	nonenzymatic generation of arsenic triglutathione from arsenite when GSH is present at concentrations 2 mM or higher. Methylation of arsenic is catalyzed by Cyt19 only when arsenic triglutathione is present in the reaction mixture	657702	
2.1.1.137	GSH	stimulatory effect on the rate of methylarsonate and dimethylarsinate production from arsenite is concentration-dependent, suppression of formation of trimethylarsine oxide	658444	
2.1.1.137	homocysteine	-	733740	
2.1.1.137	L-cysteine	-	485152	
2.1.1.137	L-cysteine	activates stronger than glutathione	485148	
2.1.1.137	thioredoxin	activates formation of methyl arsenic, dimethyl arsenic, and trimethyl arsenic	673463	
2.1.1.137	thioredoxin	dependent on, activates formation of methyl arsenic, dimethyl arsenic, and trimethyl arsenic	673463	
2.1.1.137	trimethyl-selenonium iodide	weak activator of recombinant As(III)-methyltransferase, weak inhibitor of arsenite methylation in hepatocytes	658442	
2.1.1.137	trimethylselenonium iodide	weak activator of recombinant As(III)-methyltransferase, weak inhibitor of arsenite methylation in hepatocytes	658442