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(3R)-N-[(2S)-1-hydroxy-6-[(3R)-3-isocyanobutanamido]hexan-2-yl]-3-isocyanobutanamide biosynthesis
-
-
PWY-8320
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)
-
-
PWY-7726
(5Z)-dodecenoate biosynthesis II
-
-
PWY-7858
(aminomethyl)phosphonate degradation
-
-
PWY-7805
(R)-cysteate degradation
-
-
PWY-6642
(S)-lactate fermentation to propanoate, acetate and hydrogen
-
-
PWY-8086
(S)-propane-1,2-diol degradation
-
-
PWY-7013
(S)-reticuline biosynthesis
-
-
(S)-reticuline biosynthesis I
-
-
PWY-3581
(S)-reticuline biosynthesis II
-
-
PWY-6133
1,3-propanediol biosynthesis (engineered)
-
-
PWY-7385
1,5-anhydrofructose degradation
-
-
PWY-6992
1-butanol autotrophic biosynthesis (engineered)
-
-
PWY-6886
1-methylpyrrolinium biosynthesis
-
-
PWY-5315
10-cis-heptadecenoyl-CoA degradation (yeast)
-
-
PWY-7337
10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)
-
-
PWY-7338
11-oxyandrogens biosynthesis
-
-
PWY-8202
15-epi-lipoxin biosynthesis
-
-
PWY66-393
1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)
-
-
PWY-6361
1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)
-
-
PWY-6362
1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)
-
-
PWY-6554
2,3-dihydroxybenzoate biosynthesis
-
-
PWY-5901
2-amino-3-hydroxycyclopent-2-enone biosynthesis
-
-
PWY-7536
2-arachidonoylglycerol biosynthesis
-
-
PWY-8052
2-carboxy-1,4-naphthoquinol biosynthesis
-
-
PWY-5837
2-methyl-branched fatty acid beta-oxidation
-
-
PWY-8181
2-methylpropene degradation
-
-
PWY-7778
2-nitrotoluene degradation
-
-
PWY-5641
24-epi-campesterol, fucosterol, and clionasterol biosynthesis (diatoms)
-
-
PWY-8238
3-(4-hydroxyphenyl)pyruvate biosynthesis
-
-
PWY-5886
3-dehydroquinate biosynthesis II (archaea)
-
-
PWY-6160
3-hydroxy-4-methyl-anthranilate biosynthesis I
-
-
PWY-7717
3-hydroxy-4-methyl-anthranilate biosynthesis II
-
-
PWY-7765
3-hydroxypropanoate cycle
-
-
PWY-5743
3-hydroxypropanoate/4-hydroxybutanate cycle
-
-
PWY-5789
3-methyl-branched fatty acid alpha-oxidation
-
-
PWY66-387
3-methylbutanol biosynthesis (engineered)
-
-
PWY-6871
3-phosphoinositide biosynthesis
-
-
PWY-6352
3-phosphoinositide degradation
-
-
PWY-6368
4-aminobutanoate degradation V
-
-
PWY-5022
4-hydroxy-2-nonenal detoxification
-
-
PWY-7112
4-hydroxybenzoate biosynthesis I (eukaryotes)
-
-
PWY-5754
4-oxopentanoate degradation
-
-
PWY-7948
5-aminoimidazole ribonucleotide biosynthesis I
-
-
PWY-6121
5-oxo-L-proline metabolism
-
-
PWY-7942
6-gingerol analog biosynthesis (engineered)
-
-
PWY-6920
7-(3-amino-3-carboxypropyl)-wyosine biosynthesis
-
-
PWY-7286
9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)
-
-
PWY-7340
ABH and Lewis epitopes biosynthesis from type 1 precursor disaccharide
-
-
PWY-7832
ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide
-
-
PWY-7831
Ac/N-end rule pathway
-
-
PWY-7800
acetaldehyde biosynthesis I
-
-
PWY-6333
acetate and ATP formation from acetyl-CoA III
-
-
PWY-8328
acetate conversion to acetyl-CoA
-
-
PWY0-1313
acetone degradation I (to methylglyoxal)
-
-
PWY-5451
acetone degradation III (to propane-1,2-diol)
-
-
PWY-7466
acetyl CoA biosynthesis
-
-
acetylene degradation (anaerobic)
-
-
P161-PWY
acrylonitrile degradation I
-
-
PWY-7308
adenine and adenosine salvage I
-
-
P121-PWY
adenine and adenosine salvage II
-
-
PWY-6605
adenine and adenosine salvage III
-
-
PWY-6609
adenine and adenosine salvage V
-
-
PWY-6611
adenine and adenosine salvage VI
-
-
PWY-6619
adenine salvage
-
-
PWY-6610
adenosine deoxyribonucleotides de novo biosynthesis I
-
-
PWY-7227
adenosine deoxyribonucleotides de novo biosynthesis II
-
-
PWY-7220
adenosine nucleotides degradation I
-
-
PWY-6596
adenosine nucleotides degradation II
-
-
SALVADEHYPOX-PWY
adenosine ribonucleotides de novo biosynthesis
-
-
PWY-7219
adlupulone and adhumulone biosynthesis
-
-
PWY-7857
aerobic respiration I (cytochrome c)
-
-
PWY-3781
aerobic respiration II (cytochrome c) (yeast)
-
-
PWY-7279
aerobic respiration III (alternative oxidase pathway)
-
-
PWY-4302
aerobic toluene degradation
-
-
Aflatoxin biosynthesis
-
-
Alanine, aspartate and glutamate metabolism
-
-
alkane biosynthesis II
-
-
PWY-7033
alkane oxidation
-
-
PWY-2724
all-trans-farnesol biosynthesis
-
-
PWY-6859
allantoin degradation
-
-
allantoin degradation to glyoxylate I
-
-
PWY-5694
allantoin degradation to glyoxylate III
-
-
PWY-5705
allantoin degradation to ureidoglycolate I (urea producing)
-
-
PWY-5697
allantoin degradation to ureidoglycolate II (ammonia producing)
-
-
PWY-5698
alliin metabolism
-
-
PWY-5706
allopregnanolone biosynthesis
-
-
PWY-7455
alpha-linolenate metabolites biosynthesis
-
-
PWY-8398
alpha-Linolenic acid metabolism
-
-
Amaryllidacea alkaloids biosynthesis
-
-
PWY-7826
Amino sugar and nucleotide sugar metabolism
-
-
Aminoacyl-tRNA biosynthesis
-
-
Aminobenzoate degradation
-
-
aminopropylcadaverine biosynthesis
-
-
PWY0-1303
ammonia assimilation cycle I
-
-
PWY-6963
ammonia assimilation cycle II
-
-
PWY-6964
ammonia assimilation cycle III
-
-
AMMASSIM-PWY
ammonia oxidation II (anaerobic)
-
-
P303-PWY
amygdalin and prunasin degradation
-
-
PWY-6011
anaerobic energy metabolism (invertebrates, cytosol)
-
-
PWY-7383
anaerobic energy metabolism (invertebrates, mitochondrial)
-
-
PWY-7384
anandamide biosynthesis I
-
-
PWY-8051
anandamide biosynthesis II
-
-
PWY-8053
anandamide degradation
-
-
PWY6666-1
anandamide lipoxygenation
-
-
PWY-8056
anapleurotic synthesis of oxalacetate
-
-
androgen and estrogen metabolism
-
-
androgen biosynthesis
-
-
PWY66-378
androstenedione degradation II (anaerobic)
-
-
PWY-8152
apratoxin A biosynthesis
-
-
PWY-8361
arachidonate biosynthesis
-
-
arachidonate metabolites biosynthesis
-
-
PWY-8397
Arachidonic acid metabolism
-
-
arachidonic acid metabolism
-
-
Arg/N-end rule pathway (eukaryotic)
-
-
PWY-7799
Arginine and proline metabolism
-
-
Arginine biosynthesis
-
-
aromatic biogenic amine degradation (bacteria)
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-
PWY-7431
arsenate detoxification I
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-
PWY-8264
arsenic detoxification (mammals)
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-
PWY-4202
arsenic detoxification (plants)
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-
PWY-8259
arsenic detoxification (yeast)
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-
PWY-4621
arsenite to oxygen electron transfer
-
-
PWY-4521
arsenite to oxygen electron transfer (via azurin)
-
-
PWY-7429
Ascorbate and aldarate metabolism
-
-
ascorbate glutathione cycle
-
-
PWY-2261
ascorbate recycling (cytosolic)
-
-
PWY-6370
aspartate and asparagine metabolism
-
-
aspirin triggered resolvin D biosynthesis
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-
PWY66-395
aspirin triggered resolvin E biosynthesis
-
-
PWY66-394
assimilatory sulfate reduction I
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-
SO4ASSIM-PWY
assimilatory sulfate reduction III
-
-
PWY-6683
ATP biosynthesis
-
-
PWY-7980
atromentin biosynthesis
-
-
PWY-7518
backdoor pathway of androgen biosynthesis
-
-
PWY-8200
bacterial bioluminescence
-
-
PWY-7723
baicalein degradation (hydrogen peroxide detoxification)
-
-
PWY-7214
beta-(1,4)-mannan degradation
-
-
PWY-7456
beta-1,4-D-mannosyl-N-acetyl-D-glucosamine degradation
-
-
PWY-7586
beta-alanine biosynthesis I
-
-
PWY-3981
beta-Alanine metabolism
-
-
beta-carboline biosynthesis
-
-
PWY-5877
beta-D-glucuronide and D-glucuronate degradation
-
-
PWY-7247
Betalain biosynthesis
-
-
betalamic acid biosynthesis
-
-
PWY-5394
betanidin degradation
-
-
PWY-5461
betaxanthin biosynthesis
-
-
PWY-5426
betaxanthin biosynthesis (via dopamine)
-
-
PWY-5403
Bifidobacterium shunt
-
-
P124-PWY
bile acid biosynthesis, neutral pathway
biosynthesis of Lewis epitopes (H. pylori)
-
-
PWY-7833
Biosynthesis of secondary metabolites
-
-
Biosynthesis of siderophore group nonribosomal peptides
-
-
Biosynthesis of unsaturated fatty acids
-
-
Biosynthesis of various secondary metabolites - part 3
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-
bisabolene biosynthesis (engineered)
-
-
PWY-7102
bisucaberin biosynthesis
-
-
PWY-6381
brassinolide biosynthesis I
-
-
PWY-699
brassinolide biosynthesis II
-
-
PWY-2582
Brassinosteroid biosynthesis
-
-
bupropion degradation
-
-
PWY66-241
butanol and isobutanol biosynthesis (engineered)
-
-
PWY-7396
C20 prostanoid biosynthesis
-
-
PWY66-374
C4 and CAM-carbon fixation
-
-
C4 photosynthetic carbon assimilation cycle, NAD-ME type
-
-
PWY-7115
C4 photosynthetic carbon assimilation cycle, NADP-ME type
-
-
PWY-241
C4 photosynthetic carbon assimilation cycle, PEPCK type
-
-
PWY-7117
cadaverine biosynthesis
-
-
PWY0-1601
caffeine biosynthesis I
-
-
PWY-5037
caffeine biosynthesis II (via paraxanthine)
-
-
PWY-5038
caffeine degradation III (bacteria, via demethylation)
-
-
PWY-6538
Calvin-Benson-Bassham cycle
-
-
CALVIN-PWY
camalexin biosynthesis
-
-
CAMALEXIN-SYN
canavanine biosynthesis
-
-
PWY-5
canavanine degradation
-
-
PWY-31
cannabinoid biosynthesis
-
-
PWY-5140
Caprolactam degradation
-
-
capsaicin biosynthesis
-
-
PWY-5710
Carbon fixation in photosynthetic organisms
-
-
Carbon fixation pathways in prokaryotes
-
-
catechol degradation to 2-hydroxypentadienoate I
-
-
P183-PWY
catechol degradation to 2-hydroxypentadienoate II
-
-
PWY-5419
catecholamine biosynthesis
CDP-6-deoxy-D-gulose biosynthesis
-
-
PWY-8139
CDP-diacylglycerol biosynthesis
-
-
CDP-diacylglycerol biosynthesis I
-
-
PWY-5667
CDP-diacylglycerol biosynthesis II
-
-
PWY0-1319
CDP-diacylglycerol biosynthesis III
-
-
PWY-5981
cell-surface glycoconjugate-linked phosphocholine biosynthesis
-
-
PWY-7886
ceramide and sphingolipid recycling and degradation (yeast)
-
-
PWY-7119
ceramide biosynthesis
-
-
ceramide de novo biosynthesis
-
-
PWY3DJ-12
ceramide degradation by alpha-oxidation
-
-
PWY66-388
chitin biosynthesis
-
-
PWY-6981
chitin deacetylation
-
-
PWY-7118
chitin degradation I (archaea)
-
-
PWY-6855
chitin degradation II (Vibrio)
-
-
PWY-6902
chitin degradation III (Serratia)
-
-
PWY-7822
Chloroalkane and chloroalkene degradation
-
-
Chlorocyclohexane and chlorobenzene degradation
-
-
chlorogenic acid degradation
-
-
PWY-6781
cholesterol biosynthesis
-
-
cholesterol biosynthesis (algae, late side-chain reductase)
-
-
PWY-8191
cholesterol biosynthesis (diatoms)
-
-
PWY-8239
cholesterol biosynthesis (plants, early side-chain reductase)
-
-
PWY18C3-1
cholesterol biosynthesis I
-
-
PWY66-341
cholesterol biosynthesis II (via 24,25-dihydrolanosterol)
-
-
PWY66-3
cholesterol biosynthesis III (via desmosterol)
-
-
PWY66-4
cholesterol degradation to androstenedione I (cholesterol oxidase)
-
-
PWY-6945
cholesterol degradation to androstenedione II (cholesterol dehydrogenase)
-
-
PWY-6946
choline biosynthesis III
-
-
PWY-3561
chondroitin sulfate degradation I (bacterial)
-
-
PWY-6572
chorismate biosynthesis from 3-dehydroquinate
-
-
PWY-6163
chorismate metabolism
-
-
cis-geranyl-CoA degradation
-
-
PWY-6672
Citrate cycle (TCA cycle)
-
-
CMP phosphorylation
-
-
PWY-7205
CMP-legionaminate biosynthesis I
-
-
PWY-6749
CO2 fixation in Crenarchaeota
-
-
CO2 fixation into oxaloacetate (anaplerotic)
-
-
PWYQT-4429
coenzyme B biosynthesis
-
-
P241-PWY
coenzyme M biosynthesis
-
-
coenzyme M biosynthesis II
-
-
PWY-6643
colanic acid building blocks biosynthesis
-
-
COLANSYN-PWY
colupulone and cohumulone biosynthesis
-
-
PWY-5133
complex N-linked glycan biosynthesis (plants)
-
-
PWY-7920
complex N-linked glycan biosynthesis (vertebrates)
-
-
PWY-7426
creatine biosynthesis
-
-
GLYCGREAT-PWY
creatine phosphate biosynthesis
-
-
PWY-6158
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered)
-
-
PWY-7854
curacin A biosynthesis
-
-
PWY-8358
cutin biosynthesis
-
-
PWY-321
Cutin, suberine and wax biosynthesis
-
-
Cyanoamino acid metabolism
-
-
cylindrospermopsin biosynthesis
-
-
PWY-8045
Cysteine and methionine metabolism
-
-
cytosolic NADPH production (yeast)
-
-
PWY-7268
D-Amino acid metabolism
-
-
D-arabinitol degradation I
-
-
DARABITOLUTIL-PWY
D-cycloserine biosynthesis
-
-
PWY-7274
D-galactose degradation I (Leloir pathway)
-
-
PWY-6317
D-galactose detoxification
-
-
PWY-3821
D-glucuronate degradation I
-
-
PWY-5525
d-mannose degradation
-
-
D-mannose degradation I
-
-
MANNCAT-PWY
D-mannose degradation II
-
-
PWY3O-1743
D-myo-inositol (1,3,4)-trisphosphate biosynthesis
-
-
PWY-6364
D-myo-inositol (1,4,5)-trisphosphate biosynthesis
-
-
PWY-6351
D-myo-inositol (1,4,5)-trisphosphate degradation
-
-
PWY-6363
D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis
-
-
PWY-6366
D-myo-inositol-5-phosphate metabolism
-
-
PWY-6367
D-sorbitol biosynthesis I
-
-
PWY-5054
D-xylose degradation I
-
-
XYLCAT-PWY
D-xylose degradation IV
-
-
PWY-7294
D-xylose degradation to ethylene glycol (engineered)
-
-
PWY-7178
degradation of aromatic, nitrogen containing compounds
-
-
degradation of hexoses
-
-
degradation of pentoses
-
-
degradation of sugar acids
-
-
degradation of sugar alcohols
-
-
dermatan sulfate biosynthesis
-
-
PWY-6568
dermatan sulfate degradation I (bacterial)
-
-
PWY-7646
desferrioxamine B biosynthesis
-
-
PWY-6376
desferrioxamine E biosynthesis
-
-
PWY-6375
detoxification of reactive carbonyls in chloroplasts
-
-
PWY-6786
di-homo-gamma-linolenate metabolites biosynthesis
-
-
PWY-8396
diacylglycerol and triacylglycerol biosynthesis
-
-
TRIGLSYN-PWY
diethylphosphate degradation
-
-
PWY-5491
digitoxigenin biosynthesis
-
-
PWY-6032
Diterpenoid biosynthesis
-
-
divinyl ether biosynthesis II
-
-
PWY-5409
docosahexaenoate biosynthesis III (6-desaturase, mammals)
-
-
PWY-7606
docosahexaenoate metabolites biosynthesis
-
-
PWY-8400
dolichyl-diphosphooligosaccharide biosynthesis
-
-
dopamine degradation
-
-
PWY6666-2
drosopterin and aurodrosopterin biosynthesis
-
-
PWY-7442
Drug metabolism - cytochrome P450
-
-
Drug metabolism - other enzymes
-
-
dTDP-beta-L-rhamnose biosynthesis
-
-
DTDPRHAMSYN-PWY
dTMP de novo biosynthesis (mitochondrial)
-
-
PWY66-385
dZTP biosynthesis
-
-
PWY-8289
ecdysone and 20-hydroxyecdysone biosynthesis
-
-
PWY-7300
enterobactin biosynthesis
-
-
Entner Doudoroff pathway
-
-
Entner-Doudoroff pathway I
-
-
PWY-8004
Entner-Doudoroff pathway II (non-phosphorylative)
-
-
NPGLUCAT-PWY
Entner-Doudoroff pathway III (semi-phosphorylative)
-
-
PWY-2221
ergosterol biosynthesis II
-
-
PWY-7154
ergothioneine biosynthesis I (bacteria)
-
-
PWY-7255
erythritol biosynthesis I
-
-
PWY-8372
erythritol biosynthesis II
-
-
PWY-8373
Escherichia coli serotype O:127 O antigen biosynthesis
-
-
PWY-8231
Escherichia coli serotype O:86 O antigen biosynthesis
-
-
PWY-7290
ethanol degradation I
-
-
ETOH-ACETYLCOA-ANA-PWY
ethanol degradation II
-
-
PWY66-21
ethanol degradation III
-
-
PWY66-161
ethanol degradation IV
-
-
PWY66-162
ethanolamine utilization
-
-
PWY0-1477
ethene biosynthesis I (plants)
-
-
ETHYL-PWY
ethene biosynthesis II (microbes)
-
-
PWY-6853
ethene biosynthesis III (microbes)
-
-
PWY-6854
ethene biosynthesis IV (engineered)
-
-
PWY-7126
ethene biosynthesis V (engineered)
-
-
PWY-7124
Ether lipid metabolism
-
-
eumelanin biosynthesis
-
-
PWY-6498
farnesylcysteine salvage pathway
-
-
PWY-6577
fatty acid alpha-oxidation I (plants)
-
-
PWY-2501
fatty acid beta-oxidation II (plant peroxisome)
-
-
PWY-5136
fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)
-
-
PWY-6837
fatty acid beta-oxidation VI (mammalian peroxisome)
-
-
PWY66-391
fatty acid beta-oxidation VII (yeast peroxisome)
-
-
PWY-7288
Fatty acid biosynthesis
-
-
fatty acid biosynthesis initiation (type I)
-
-
PWY-5966-1
Fatty acid degradation
-
-
fatty acid salvage
-
-
PWY-7094
Fe(II) oxidation
-
-
PWY-6692
FeMo cofactor biosynthesis
-
-
PWY-7710
ferrichrome A biosynthesis
-
-
PWY-7571
firefly bioluminescence
-
-
PWY-7913
Flavone and flavonol biosynthesis
-
-
fluoroacetate and fluorothreonine biosynthesis
-
-
PWY-6644
folate transformations I
-
-
PWY-2201
folate transformations II (plants)
-
-
PWY-3841
folate transformations III (E. coli)
-
-
1CMET2-PWY
formaldehyde assimilation I (serine pathway)
-
-
PWY-1622
formaldehyde assimilation II (assimilatory RuMP Cycle)
-
-
PWY-1861
formaldehyde assimilation III (dihydroxyacetone cycle)
-
-
P185-PWY
formaldehyde oxidation
-
-
formaldehyde oxidation I
-
-
RUMP-PWY
formaldehyde oxidation II (glutathione-dependent)
-
-
PWY-1801
formaldehyde oxidation VII (THF pathway)
-
-
PWY-7909
formate assimilation into 5,10-methylenetetrahydrofolate
-
-
PWY-1722
fructose 2,6-bisphosphate biosynthesis
-
-
PWY66-423
Fructose and mannose metabolism
-
-
GABA shunt I
-
-
GLUDEG-I-PWY
GABA shunt II
-
-
PWY-8346
gamma-glutamyl cycle
-
-
PWY-4041
gamma-linolenate biosynthesis II (animals)
-
-
PWY-6000
ganglio-series glycosphingolipids biosynthesis
-
-
PWY-7836
GDP-alpha-D-glucose biosynthesis
-
-
PWY-5661
GDP-mannose biosynthesis
-
-
PWY-5659
gliotoxin biosynthesis
-
-
PWY-7533
glucocorticoid biosynthesis
-
-
PWY66-381
gluconeogenesis I
-
-
GLUCONEO-PWY
gluconeogenesis II (Methanobacterium thermoautotrophicum)
-
-
PWY-6142
gluconeogenesis III
-
-
PWY66-399
glucose and glucose-1-phosphate degradation
-
-
GLUCOSE1PMETAB-PWY
glucose degradation (oxidative)
-
-
DHGLUCONATE-PYR-CAT-PWY
glucosylglycerol biosynthesis
-
-
PWY-7902
glutamate and glutamine metabolism
-
-
glutaminyl-tRNAgln biosynthesis via transamidation
-
-
PWY-5921
glutathione biosynthesis
-
-
GLUTATHIONESYN-PWY
glutathione degradation (DUG pathway)
-
-
PWY-7559
Glutathione metabolism
-
-
glutathione metabolism
-
-
glutathione-mediated detoxification I
-
-
PWY-4061
glutathione-mediated detoxification II
-
-
PWY-6842
glutathione-peroxide redox reactions
-
-
PWY-4081
glycerol degradation I
-
-
PWY-4261
glycerol degradation to butanol
-
-
PWY-7003
glycerol-3-phosphate shuttle
-
-
PWY-6118
glycerol-3-phosphate to cytochrome bo oxidase electron transfer
-
-
PWY0-1561
glycerol-3-phosphate to fumarate electron transfer
-
-
PWY0-1582
glycerol-3-phosphate to hydrogen peroxide electron transport
-
-
PWY0-1591
Glycerolipid metabolism
-
-
glycerophosphodiester degradation
-
-
PWY-6952
Glycerophospholipid metabolism
-
-
glycine betaine biosynthesis
-
-
glycine betaine degradation I
-
-
PWY-3661
glycine betaine degradation II (mammalian)
-
-
PWY-3661-1
glycine betaine degradation III
-
-
PWY-8325
glycine biosynthesis I
-
-
GLYSYN-PWY
glycine biosynthesis II
-
-
GLYCINE-SYN2-PWY
glycine cleavage
-
-
GLYCLEAV-PWY
Glycine, serine and threonine metabolism
-
-
glycogen biosynthesis
-
-
glycogen biosynthesis I (from ADP-D-Glucose)
-
-
GLYCOGENSYNTH-PWY
glycogen biosynthesis II (from UDP-D-Glucose)
-
-
PWY-5067
glycogen biosynthesis III (from alpha-maltose 1-phosphate)
-
-
PWY-7900
glycogen degradation I
-
-
GLYCOCAT-PWY
glycogen degradation II
-
-
PWY-5941
glycolate and glyoxylate degradation
-
-
Glycolysis / Gluconeogenesis
-
-
glycolysis I (from glucose 6-phosphate)
-
-
GLYCOLYSIS
glycolysis II (from fructose 6-phosphate)
-
-
PWY-5484
glycolysis III (from glucose)
-
-
ANAGLYCOLYSIS-PWY
glycolysis IV
-
-
PWY-1042
glycolysis V (Pyrococcus)
-
-
P341-PWY
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
-
-
Glycosaminoglycan biosynthesis - heparan sulfate / heparin
-
-
Glycosaminoglycan degradation
-
-
Glycosphingolipid biosynthesis - ganglio series
-
-
Glycosphingolipid biosynthesis - globo and isoglobo series
-
-
Glycosphingolipid biosynthesis - lacto and neolacto series
-
-
Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
-
-
Glyoxylate and dicarboxylate metabolism
-
-
glyoxylate assimilation
-
-
PWY-5744
glyoxylate cycle
-
-
GLYOXYLATE-BYPASS
glyphosate degradation III
-
-
PWY-7807
guadinomine B biosynthesis
-
-
PWY-7693
guanine and guanosine salvage I
-
-
PWY-6620
guanine and guanosine salvage II
-
-
PWY-6599
guanosine deoxyribonucleotides de novo biosynthesis I
-
-
PWY-7226
guanosine deoxyribonucleotides de novo biosynthesis II
-
-
PWY-7222
guanosine nucleotides degradation I
-
-
PWY-6607
guanosine nucleotides degradation II
-
-
PWY-6606
guanosine nucleotides degradation III
-
-
PWY-6608
guanosine ribonucleotides de novo biosynthesis
-
-
PWY-7221
H. pylori 26695 O-antigen biosynthesis
-
-
PWY2DNV-5
heme b biosynthesis I (aerobic)
-
-
HEME-BIOSYNTHESIS-II
heme b biosynthesis II (oxygen-independent)
-
-
HEMESYN2-PWY
heme b biosynthesis V (aerobic)
-
-
HEME-BIOSYNTHESIS-II-1
heme degradation I
-
-
PWY-5874
heparan sulfate biosynthesis
-
-
PWY-6558
heparan sulfate degradation
-
-
PWY-7651
heparin degradation
-
-
PWY-7644
heterolactic fermentation
-
-
P122-PWY
histamine degradation
-
-
PWY-6181
homocysteine and cysteine interconversion
-
-
PWY-801
homoglutathione biosynthesis
-
-
PWY-6840
homospermidine biosynthesis I
-
-
PWY-5907
homospermidine biosynthesis II
-
-
PWY-8149
hyaluronan degradation
-
-
PWY-7645
hydrogen sulfide biosynthesis II (mammalian)
-
-
PWY66-426
hydrogen to fumarate electron transfer
-
-
PWY0-1576
hydroxycinnamic acid serotonin amides biosynthesis
-
-
PWY-5473
hydroxycinnamic acid tyramine amides biosynthesis
-
-
PWY-5474
hypoglycin biosynthesis
-
-
PWY-5826
hypotaurine degradation
-
-
PWY-7387
icosapentaenoate biosynthesis II (6-desaturase, mammals)
-
-
PWY-7049
icosapentaenoate biosynthesis III (8-desaturase, mammals)
-
-
PWY-7724
icosapentaenoate metabolites biosynthesis
-
-
PWY-8399
incomplete reductive TCA cycle
-
-
P42-PWY
indole glucosinolate activation (intact plant cell)
-
-
PWYQT-4477
indole-3-acetate biosynthesis II
-
-
PWY-581
indole-3-acetate biosynthesis III (bacteria)
-
-
PWY-3161
indole-3-acetate biosynthesis IV (bacteria)
-
-
PWY-5025
indole-3-acetate biosynthesis VI (bacteria)
-
-
TRPIAACAT-PWY
inosine 5'-phosphate degradation
-
-
PWY-5695
inosine-5'-phosphate biosynthesis I
-
-
PWY-6123
inosine-5'-phosphate biosynthesis II
-
-
PWY-6124
inosine-5'-phosphate biosynthesis III
-
-
PWY-7234
Inositol phosphate metabolism
-
-
Insect hormone biosynthesis
-
-
inulin degradation
-
-
PWY-8314
isoprene biosynthesis II (engineered)
-
-
PWY-7391
isoprenoid biosynthesis
-
-
Isoquinoline alkaloid biosynthesis
-
-
jadomycin biosynthesis
-
-
PWY-6679
jasmonic acid biosynthesis
-
-
PWY-735
justicidin B biosynthesis
-
-
PWY-6824
ketogenesis
-
-
PWY66-367
L-alanine biosynthesis II
-
-
ALANINE-SYN2-PWY
L-alanine degradation II (to D-lactate)
-
-
ALACAT2-PWY
L-alanine degradation III
-
-
ALANINE-DEG3-PWY
L-alanine degradation V (oxidative Stickland reaction)
-
-
PWY-8189
L-alanine degradation VI (reductive Stickland reaction)
-
-
PWY-8188
L-arabinose degradation IV
-
-
PWY-7295
L-arginine biosynthesis I (via L-ornithine)
-
-
ARGSYN-PWY
L-arginine biosynthesis II (acetyl cycle)
-
-
ARGSYNBSUB-PWY
L-arginine biosynthesis III (via N-acetyl-L-citrulline)
-
-
PWY-5154
L-arginine biosynthesis IV (archaea)
-
-
PWY-7400
L-arginine degradation I (arginase pathway)
-
-
ARGASEDEG-PWY
L-arginine degradation II (AST pathway)
-
-
AST-PWY
L-arginine degradation VI (arginase 2 pathway)
-
-
ARG-PRO-PWY
L-arginine degradation VII (arginase 3 pathway)
-
-
ARG-GLU-PWY
L-arginine degradation X (arginine monooxygenase pathway)
-
-
ARGDEG-V-PWY
L-arginine degradation XIII (reductive Stickland reaction)
-
-
PWY-8187
L-arginine degradation XIV (oxidative Stickland reaction)
-
-
PWY-6344
L-ascorbate biosynthesis IV (animals, D-glucuronate pathway)
-
-
PWY3DJ-35471
L-ascorbate biosynthesis VI (plants, myo-inositol pathway)
-
-
PWY-8142
L-ascorbate degradation I (bacterial, anaerobic)
-
-
PWY0-301
L-asparagine biosynthesis III (tRNA-dependent)
-
-
PWY490-4
L-asparagine degradation III (mammalian)
-
-
ASPARAGINE-DEG1-PWY-1
L-aspartate biosynthesis
-
-
ASPARTATESYN-PWY
L-aspartate degradation I
-
-
ASPARTATE-DEG1-PWY
L-aspartate degradation II (aerobic)
-
-
PWY-8291
L-aspartate degradation III (anaerobic)
-
-
PWY-8294
L-carnitine degradation II
-
-
PWY-3641
L-citrulline biosynthesis
-
-
CITRULBIO-PWY
L-citrulline degradation
-
-
CITRULLINE-DEG-PWY
L-cysteine biosynthesis I
-
-
CYSTSYN-PWY
L-cysteine biosynthesis III (from L-homocysteine)
-
-
HOMOCYSDEGR-PWY
L-cysteine biosynthesis VI (reverse transsulfuration)
-
-
PWY-I9
L-cysteine biosynthesis VII (from S-sulfo-L-cysteine)
-
-
PWY-7870
L-cysteine degradation III
-
-
PWY-5329
L-dopa and L-dopachrome biosynthesis
-
-
PWY-6481
L-dopa degradation II (bacterial)
-
-
PWY-8110
L-glutamate biosynthesis I
-
-
GLUTSYN-PWY
L-glutamate biosynthesis II
-
-
GLUTAMATE-SYN2-PWY
L-glutamate biosynthesis IV
-
-
GLUGLNSYN-PWY
L-glutamate degradation I
-
-
GLUTAMATE-DEG1-PWY
L-glutamate degradation II
-
-
GLUTDEG-PWY
L-glutamate degradation IX (via 4-aminobutanoate)
-
-
PWY0-1305
L-glutamate degradation V (via hydroxyglutarate)
-
-
P162-PWY
L-glutamate degradation X
-
-
PWY-5766
L-glutamate degradation XI (reductive Stickland reaction)
-
-
PWY-8190
L-glutamine biosynthesis I
-
-
GLNSYN-PWY
L-glutamine degradation I
-
-
GLUTAMINDEG-PWY
L-glutamine degradation II
-
-
GLUTAMINEFUM-PWY
L-histidine degradation I
-
-
HISDEG-PWY
L-histidine degradation II
-
-
PWY-5028
L-histidine degradation III
-
-
PWY-5030
L-histidine degradation V
-
-
PWY-5031
L-histidine degradation VI
-
-
HISHP-PWY
L-isoleucine biosynthesis V
-
-
PWY-5108
L-isoleucine degradation I
-
-
ILEUDEG-PWY
L-isoleucine degradation II
-
-
PWY-5078
L-lactaldehyde degradation
-
-
L-leucine degradation III
-
-
PWY-5076
L-lysine biosynthesis IV
-
-
LYSINE-AMINOAD-PWY
L-lysine biosynthesis V
-
-
PWY-3081
L-lysine degradation I
-
-
PWY0-461
L-lysine degradation II (L-pipecolate pathway)
-
-
PWY66-425
L-lysine degradation V
-
-
PWY-5283
L-lysine degradation X
-
-
PWY-6328
L-lysine degradation XI
-
-
LYSINE-DEG1-PWY
L-malate degradation II
-
-
PWY-7686
L-methionine degradation I (to L-homocysteine)
-
-
METHIONINE-DEG1-PWY
L-methionine degradation III
-
-
PWY-5082
L-Ndelta-acetylornithine biosynthesis
-
-
PWY-6922
L-ornithine biosynthesis I
-
-
GLUTORN-PWY
L-ornithine biosynthesis II
-
-
ARGININE-SYN4-PWY
L-phenylalanine biosynthesis I
-
-
PHESYN
L-phenylalanine degradation I (aerobic)
-
-
PHENYLALANINE-DEG1-PWY
L-phenylalanine degradation II (anaerobic)
-
-
ANAPHENOXI-PWY
L-phenylalanine degradation III
-
-
PWY-5079
L-phenylalanine degradation IV (mammalian, via side chain)
-
-
PWY-6318
L-phenylalanine degradation V
-
-
PWY-7158
L-phenylalanine degradation VI (reductive Stickland reaction)
-
-
PWY-8014
L-proline biosynthesis III (from L-ornithine)
-
-
PWY-3341
L-proline biosynthesis IV
-
-
PWY-4281
L-proline degradation I
-
-
PROUT-PWY
L-selenocysteine biosynthesis I (bacteria)
-
-
PWY0-901
L-serine biosynthesis I
-
-
SERSYN-PWY
L-serine biosynthesis II
-
-
PWY-8011
L-threonine degradation III (to methylglyoxal)
-
-
THRDLCTCAT-PWY
L-tryptophan degradation I (via anthranilate)
-
-
TRPCAT-PWY
L-tryptophan degradation IV (via indole-3-lactate)
-
-
TRPKYNCAT-PWY
L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
-
-
PWY-5651
L-tryptophan degradation V (side chain pathway)
-
-
PWY-3162
L-tryptophan degradation VI (via tryptamine)
-
-
PWY-3181
L-tryptophan degradation VIII (to tryptophol)
-
-
PWY-5081
L-tryptophan degradation X (mammalian, via tryptamine)
-
-
PWY-6307
L-tryptophan degradation XI (mammalian, via kynurenine)
-
-
PWY-6309
L-tryptophan degradation XIII (reductive Stickland reaction)
-
-
PWY-8017
L-tyrosine biosynthesis I
-
-
TYRSYN
L-tyrosine biosynthesis IV
-
-
PWY-6134
L-tyrosine degradation I
-
-
TYRFUMCAT-PWY
L-tyrosine degradation II
-
-
PWY-5151
L-tyrosine degradation III
-
-
PWY3O-4108
L-tyrosine degradation IV (to 4-methylphenol)
-
-
PWY-7514
L-tyrosine degradation V (reductive Stickland reaction)
-
-
PWY-8016
L-valine degradation II
-
-
PWY-5057
lacto-series glycosphingolipids biosynthesis
-
-
PWY-7839
lanosterol biosynthesis
-
-
PWY-6132
leukotriene biosynthesis
-
-
PWY66-375
Limonene and pinene degradation
-
-
limonene degradation IV (anaerobic)
-
-
PWY-8029
linoleate biosynthesis II (animals)
-
-
PWY-6001
linoleate metabolites biosynthesis
-
-
PWY-8395
Linoleic acid metabolism
-
-
lipid A-core biosynthesis (E. coli K-12)
-
-
LIPA-CORESYN-PWY
lipid IVA biosynthesis (2,3-diamino-2,3-dideoxy-D-glucopyranose-containing)
-
-
PWY2B4Q-4
lipid IVA biosynthesis (E. coli)
-
-
NAGLIPASYN-PWY
lipid IVA biosynthesis (generic)
-
-
PWY-8283
lipid IVA biosynthesis (H. pylori)
-
-
PWYI-14
lipid IVA biosynthesis (P. gingivalis)
-
-
PWY-8245
lipid IVA biosynthesis (P. putida)
-
-
PWY-8073
lipid IVA biosynthesis (Vibrio cholerae serogroup O1 El Tor)
-
-
PWY2G6Z-2
Lipopolysaccharide biosynthesis
-
-
lipoxin biosynthesis
-
-
PWY66-392
long chain fatty acid ester synthesis (engineered)
-
-
PWY-6873
long-chain fatty acid activation
-
-
PWY-5143
lupanine biosynthesis
-
-
PWY-5468
lupulone and humulone biosynthesis
-
-
PWY-5132
luteolin triglucuronide degradation
-
-
PWY-7445
malate/L-aspartate shuttle pathway
-
-
MALATE-ASPARTATE-SHUTTLE-PWY
manganese oxidation I
-
-
PWY-6591
mannitol biosynthesis
-
-
PWY-3881
mannitol degradation II
-
-
PWY-3861
Mannose type O-glycan biosynthesis
-
-
maresin biosynthesis
-
-
PWY-8356
matairesinol biosynthesis
-
-
PWY-5466
melatonin degradation I
-
-
PWY-6398
melatonin degradation II
-
-
PWY-6399
metabolism of amino sugars and derivatives
-
-
metabolism of disaccharids
-
-
Metabolism of xenobiotics by cytochrome P450
-
-
Methanobacterium thermoautotrophicum biosynthetic metabolism
-
-
PWY-6146
methanofuran biosynthesis
-
-
PWY-5254
methanol oxidation to formaldehyde IV
-
-
PWY-5506
methiin metabolism
-
-
PWY-7614
methionine metabolism
-
-
methyl indole-3-acetate interconversion
-
-
PWY-6303
methyl ketone biosynthesis (engineered)
-
-
PWY-7007
methyl phomopsenoate biosynthesis
-
-
PWY-7721
methylsalicylate degradation
-
-
PWY18C3-24
methylwyosine biosynthesis
-
-
PWY-7285
mevalonate metabolism
-
-
mevalonate pathway I (eukaryotes and bacteria)
-
-
PWY-922
mevalonate pathway II (haloarchaea)
-
-
PWY-6174
mevalonate pathway III (Thermoplasma)
-
-
PWY-7524
mevalonate pathway IV (archaea)
-
-
PWY-8125
Microbial metabolism in diverse environments
-
-
mitochondrial L-carnitine shuttle
-
-
PWY-6111
mitochondrial NADPH production (yeast)
-
-
PWY-7269
mixed acid fermentation
-
-
FERMENTATION-PWY
monoacylglycerol metabolism (yeast)
-
-
PWY-7420
mRNA capping I
-
-
PWY-7375
mucin core 1 and core 2 O-glycosylation
-
-
PWY-7433
mucin core 3 and core 4 O-glycosylation
-
-
PWY-7435
Mucin type O-glycan biosynthesis
-
-
muropeptide degradation
-
-
PWY0-1546
mycolyl-arabinogalactan-peptidoglycan complex biosynthesis
-
-
PWY-6397
myo-inositol biosynthesis
N-3-oxalyl-L-2,3-diaminopropanoate biosynthesis
-
-
PWY-8071
N-acetylneuraminate and N-acetylmannosamine degradation I
-
-
PWY0-1324
N-acetylneuraminate and N-acetylmannosamine degradation II
-
-
PWY-7581
N-Glycan biosynthesis
-
-
N-hydroxy-L-pipecolate biosynthesis
-
-
PWY-7861
NAD phosphorylation and dephosphorylation
-
-
NADPHOS-DEPHOS-PWY
NAD salvage (plants)
-
-
PWY-5381
NAD salvage pathway I (PNC VI cycle)
-
-
PYRIDNUCSAL-PWY
NAD salvage pathway III (to nicotinamide riboside)
-
-
NAD-BIOSYNTHESIS-II
NAD salvage pathway V (PNC V cycle)
-
-
PWY3O-4107
NAD(P)/NADPH interconversion
-
-
PWY-5083
NADH to cytochrome bd oxidase electron transfer I
-
-
PWY0-1334
NADH to cytochrome bo oxidase electron transfer I
-
-
PWY0-1335
NADH to fumarate electron transfer
-
-
PWY0-1336
NADPH to cytochrome c oxidase via plastocyanin
-
-
PWY-8271
Naphthalene degradation
-
-
Neomycin, kanamycin and gentamicin biosynthesis
-
-
Nicotinate and nicotinamide metabolism
-
-
nicotine degradation IV
-
-
PWY66-201
nicotine degradation V
-
-
PWY66-221
nitrate reduction I (denitrification)
-
-
DENITRIFICATION-PWY
nitrate reduction IX (dissimilatory)
-
-
PWY0-1581
nitrate reduction VII (denitrification)
-
-
PWY-6748
nitrate reduction X (dissimilatory, periplasmic)
-
-
PWY0-1584
nitric oxide biosynthesis II (mammals)
-
-
PWY-4983
nitrifier denitrification
-
-
PWY-7084
nitrite-dependent anaerobic methane oxidation
-
-
PWY-6523
nitrogen fixation I (ferredoxin)
-
-
N2FIX-PWY
nitrogen remobilization from senescing leaves
-
-
PWY-6549
Nitrotoluene degradation
-
-
nocardicin A biosynthesis
-
-
PWY-7797
noradrenaline and adrenaline degradation
-
-
PWY-6342
Novobiocin biosynthesis
-
-
nucleoside and nucleotide degradation (archaea)
-
-
PWY-5532
O-antigen biosynthesis
-
-
O-Antigen nucleotide sugar biosynthesis
-
-
o-diquinones biosynthesis
-
-
PWY-6752
octopamine biosynthesis
-
-
PWY-7297
oleandomycin activation/inactivation
-
-
PWY-6972
oleate beta-oxidation
-
-
PWY0-1337
oleate beta-oxidation (isomerase-dependent, yeast)
-
-
PWY-7291
oleate biosynthesis I (plants)
-
-
PWY-5147
oleate biosynthesis II (animals and fungi)
-
-
PWY-5996
oleate biosynthesis III (cyanobacteria)
-
-
PWY-7587
One carbon pool by folate
-
-
ophthalmate biosynthesis
-
-
PWY-8043
Other glycan degradation
-
-
Other types of O-glycan biosynthesis
-
-
oxidative decarboxylation of pyruvate
-
-
Oxidative phosphorylation
-
-
oxidative phosphorylation
-
-
palmitate biosynthesis II (type II fatty acid synthase)
-
-
PWY-5971
palmitate biosynthesis III
-
-
PWY-8279
palmitoleate biosynthesis IV (fungi and animals)
-
-
PWY3O-1801
palmitoyl ethanolamide biosynthesis
-
-
PWY-8055
Pantothenate and CoA biosynthesis
-
-
pantothenate biosynthesis
-
-
partial TCA cycle (obligate autotrophs)
-
-
PWY-5913
Penicillin and cephalosporin biosynthesis
-
-
pentachlorophenol degradation
-
-
PCPDEG-PWY
Pentose and glucuronate interconversions
-
-
Pentose phosphate pathway
-
-
pentose phosphate pathway
-
-
pentose phosphate pathway (non-oxidative branch) I
-
-
NONOXIPENT-PWY
pentose phosphate pathway (non-oxidative branch) II
-
-
PWY-8178
pentose phosphate pathway (oxidative branch) I
-
-
OXIDATIVEPENT-PWY
pentose phosphate pathway (partial)
-
-
P21-PWY
peptido-conjugates in tissue regeneration biosynthesis
-
-
PWY-8355
Peptidoglycan biosynthesis
-
-
peptidoglycan biosynthesis
-
-
peptidoglycan biosynthesis II (staphylococci)
-
-
PWY-5265
peptidoglycan biosynthesis IV (Enterococcus faecium)
-
-
PWY-6471
peptidoglycan maturation (meso-diaminopimelate containing)
-
-
PWY0-1586
peptidoglycan recycling I
-
-
PWY0-1261
peptidoglycan recycling II
-
-
PWY-7883
Phenylalanine metabolism
-
-
phenylalanine metabolism
-
-
Phenylalanine, tyrosine and tryptophan biosynthesis
-
-
phenylethanol biosynthesis
-
-
PWY-5751
phenylethylamine degradation I
-
-
2PHENDEG-PWY
Phenylpropanoid biosynthesis
-
-
pheomelanin biosynthesis
-
-
PWY-7917
phosphate acquisition
-
-
PWY-6348
phosphatidate biosynthesis (yeast)
-
-
PWY-7411
phosphatidate metabolism, as a signaling molecule
-
-
PWY-7039
phosphatidylcholine acyl editing
-
-
PWY-6803
phosphatidylcholine biosynthesis I
-
-
PWY3O-450
phosphatidylcholine resynthesis via glycerophosphocholine
-
-
PWY-7367
phosphatidylethanolamine bioynthesis
-
-
phospholipases
-
-
LIPASYN-PWY
phospholipid remodeling (phosphatidate, yeast)
-
-
PWY-7417
phospholipid remodeling (phosphatidylcholine, yeast)
-
-
PWY-7416
phospholipid remodeling (phosphatidylethanolamine, yeast)
-
-
PWY-7409
phosphopantothenate biosynthesis I
-
-
PANTO-PWY
photorespiration I
-
-
PWY-181
photorespiration II
-
-
PWY-8362
photorespiration III
-
-
PWY-8363
photosynthesis light reactions
-
-
PWY-101
photosynthetic 3-hydroxybutanoate biosynthesis (engineered)
-
-
PWY-7218
phytate degradation I
-
-
PWY-4702
phytochelatins biosynthesis
-
-
PWY-6745
phytochromobilin biosynthesis
-
-
PWY-7170
phytol degradation
-
-
PWY66-389
phytosterol biosynthesis (plants)
-
-
PWY-2541
pinitol biosynthesis I
-
-
PWY-6738
plasmalogen biosynthesis I (aerobic)
-
-
PWY-7782
plasmalogen degradation
-
-
PWY-7783
poly-hydroxy fatty acids biosynthesis
-
-
PWY-6710
Porphyrin and chlorophyll metabolism
-
-
ppGpp metabolism
-
-
PPGPPMET-PWY
Primary bile acid biosynthesis
-
-
procollagen hydroxylation and glycosylation
-
-
PWY-7894
propanethial S-oxide biosynthesis
-
-
PWY-5707
propanoate fermentation to 2-methylbutanoate
-
-
PWY-5109
Propanoate metabolism
-
-
propanoyl-CoA degradation II
-
-
PWY-7574
propionate fermentation
-
-
protectin biosynthesis
-
-
PWY-8357
protective electron sinks in the thylakoid membrane (PSII to PTOX)
-
-
PWY1YI0-7
protein N-glycosylation (Haloferax volcanii)
-
-
PWY-7661
protein N-glycosylation initial phase (eukaryotic)
-
-
MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
protein N-glycosylation processing phase (endoplasmic reticulum, yeast)
-
-
PWY-7918
protein N-glycosylation processing phase (plants and animals)
-
-
PWY-7919
protein O-mannosylation I (yeast)
-
-
PWY-7921
protein O-mannosylation II (mammals, core M1 and core M2)
-
-
PWY-7922
protein O-mannosylation III (mammals, core M3)
-
-
PWY-7979
protein O-[N-acetyl]-glucosylation
-
-
PWY-7437
protein S-nitrosylation and denitrosylation
-
-
PWY-7798
protein ubiquitination
-
-
PWY-7511
psilocybin biosynthesis
-
-
PWY-7936
purine deoxyribonucleosides degradation I
-
-
PWY-7179
purine deoxyribonucleosides degradation II
-
-
PWY-7179-1
purine deoxyribonucleosides salvage
-
-
PWY-7224
purine nucleobases degradation I (anaerobic)
-
-
P164-PWY
purine nucleobases degradation II (anaerobic)
-
-
PWY-5497
purine ribonucleosides degradation
-
-
PWY0-1296
putrescine biosynthesis III
-
-
PWY-46
putrescine degradation III
-
-
PWY-0
pyrimidine deoxyribonucleosides degradation
-
-
PWY-7181
pyrimidine deoxyribonucleosides salvage
-
-
PWY-7199
pyrimidine deoxyribonucleotide phosphorylation
-
-
PWY-7197
pyrimidine deoxyribonucleotides biosynthesis from CTP
-
-
PWY-7210
pyrimidine deoxyribonucleotides de novo biosynthesis I
-
-
PWY-7184
pyrimidine deoxyribonucleotides de novo biosynthesis II
-
-
PWY-7187
pyrimidine deoxyribonucleotides de novo biosynthesis III
-
-
PWY-6545
pyrimidine deoxyribonucleotides de novo biosynthesis IV
-
-
PWY-7198
pyrimidine deoxyribonucleotides dephosphorylation
-
-
PWY-7206
Pyrimidine metabolism
-
-
pyrimidine metabolism
-
-
pyrimidine ribonucleosides degradation
-
-
PWY0-1295
pyrimidine ribonucleosides salvage I
-
-
PWY-7193
pyrimidine ribonucleosides salvage II
-
-
PWY-6556
pyruvate decarboxylation to acetyl CoA I
-
-
PYRUVDEHYD-PWY
pyruvate decarboxylation to acetyl CoA II
-
-
PWY-6970
pyruvate fermentation to (R)-lactate
-
-
PWY-8274
pyruvate fermentation to (S)-lactate
-
-
PWY-5481
pyruvate fermentation to butanol I
-
-
PWY-6583
pyruvate fermentation to ethanol I
-
-
PWY-5480
pyruvate fermentation to ethanol II
-
-
PWY-5486
pyruvate fermentation to ethanol III
-
-
PWY-6587
pyruvate fermentation to isobutanol (engineered)
-
-
PWY-7111
pyruvate fermentation to propanoate I
-
-
P108-PWY
queuosine biosynthesis I (de novo)
-
-
PWY-6700
queuosine biosynthesis II (queuine salvage)
-
-
PWY-8105
queuosine biosynthesis III (queuosine salvage)
-
-
PWY-8106
reactive oxygen species degradation
-
-
DETOX1-PWY-1
reductive acetyl coenzyme A pathway
-
-
reductive acetyl coenzyme A pathway I (homoacetogenic bacteria)
-
-
CODH-PWY
reductive glycine pathway of autotrophic CO2 fixation
-
-
PWY-8303
reductive TCA cycle I
-
-
P23-PWY
reductive TCA cycle II
-
-
PWY-5392
resolvin D biosynthesis
-
-
PWY66-397
retinoate biosynthesis I
-
-
PWY-6872
retinol biosynthesis
-
-
PWY-6857
Riboflavin metabolism
-
-
rosmarinic acid biosynthesis I
-
-
PWY-5048
rosmarinic acid biosynthesis II
-
-
PWY-5049
Rubisco shunt
-
-
PWY-5723
S-(6-hydroxy-4-methylhexan-4-yl)-L-cysteinylglycine biosynthesis
-
-
PWY-8301
S-adenosyl-L-methionine salvage II
-
-
PWY-5041
salicylate biosynthesis I
-
-
PWY-6406
salicylate biosynthesis II
-
-
PWY-8321
salidroside biosynthesis
-
-
PWY-6802
salinosporamide A biosynthesis
-
-
PWY-6627
Salmonella enterica serotype O:13 O antigen biosynthesis
-
-
PWY-8230
secologanin and strictosidine biosynthesis
-
-
PWY-5290
sedoheptulose bisphosphate bypass
-
-
PWY0-1517
seleno-amino acid biosynthesis (plants)
-
-
PWY-6936
Selenocompound metabolism
-
-
selenocysteine biosynthesis
-
-
serine racemization
-
-
PWY-8140
serotonin and melatonin biosynthesis
-
-
PWY-6030
serotonin degradation
-
-
PWY-6313
sesamin biosynthesis
-
-
PWY-5469
sitosterol degradation to androstenedione
-
-
PWY-6948
sophorolipid biosynthesis
-
-
SOPHOROSYLOXYDOCOSANOATE-SYN-PWY
sophorosyloxydocosanoate deacetylation
-
-
SOPHOROSYLOXYDOCOSANOATE-DEG-PWY
sorgoleone biosynthesis
-
-
PWY-5987
spermidine biosynthesis I
-
-
BSUBPOLYAMSYN-PWY
spermidine biosynthesis III
-
-
PWY-6834
spermine biosynthesis
-
-
ARGSPECAT-PWY
sphingolipid biosynthesis (mammals)
-
-
PWY-7277
sphingolipid biosynthesis (plants)
-
-
PWY-5129
Sphingolipid metabolism
-
-
sphingomyelin metabolism
-
-
PWY3DJ-11281
sphingosine and sphingosine-1-phosphate metabolism
-
-
PWY3DJ-11470
sphingosine metabolism
-
-
sporopollenin precursors biosynthesis
-
-
PWY-6733
stachyose degradation
-
-
PWY-6527
Starch and sucrose metabolism
-
-
starch biosynthesis
-
-
PWY-622
starch degradation I
-
-
PWY-842
starch degradation III
-
-
PWY-6731
starch degradation V
-
-
PWY-6737
stearate biosynthesis I (animals)
-
-
PWY-5972
stearate biosynthesis II (bacteria and plants)
-
-
PWY-5989
stearate biosynthesis IV
-
-
PWY-8280
stellatic acid biosynthesis
-
-
PWY-7736
Steroid hormone biosynthesis
-
-
sterol biosynthesis (methylotrophs)
-
-
PWY-8026
sterol:steryl ester interconversion (yeast)
-
-
PWY-7424
stigma estolide biosynthesis
-
-
PWY-6453
streptomycin biosynthesis
-
-
PWY-5940
Streptomycin biosynthesis
-
-
suberin monomers biosynthesis
-
-
PWY-1121
succinate to chytochrome c oxidase via cytochrome c6
-
-
PWY1YI0-2
succinate to cytochrome bd oxidase electron transfer
-
-
PWY0-1353
succinate to cytochrome bo oxidase electron transfer
-
-
PWY0-1329
succinate to cytochrome c oxidase via plastocyanin
-
-
PWY1YI0-3
succinate to plastoquinol oxidase
-
-
PWY1YI0-8
sucrose biosynthesis I (from photosynthesis)
-
-
SUCSYN-PWY
sucrose biosynthesis II
-
-
PWY-7238
sucrose biosynthesis III
-
-
PWY-7347
sucrose degradation II (sucrose synthase)
-
-
PWY-3801
sucrose degradation III (sucrose invertase)
-
-
PWY-621
sucrose degradation IV (sucrose phosphorylase)
-
-
PWY-5384
sucrose degradation V (sucrose alpha-glucosidase)
-
-
PWY66-373
sulfated glycosaminoglycan metabolism
-
-
sulfide oxidation IV (mitochondria)
-
-
PWY-7927
sulfolactate degradation III
-
-
PWY-6638
sulfopterin metabolism
-
-
sulfur volatiles biosynthesis
-
-
PWY-6736
superoxide radicals degradation
-
-
DETOX1-PWY
superpathway of fermentation (Chlamydomonas reinhardtii)
-
-
PWY4LZ-257
superpathway of glucose and xylose degradation
-
-
PWY-6901
superpathway of glycolysis and the Entner-Doudoroff pathway
-
-
GLYCOLYSIS-E-D
superpathway of glyoxylate cycle and fatty acid degradation
-
-
PWY-561
superpathway of methylsalicylate metabolism
-
-
PWY18C3-25
superpathway of ornithine degradation
-
-
ORNDEG-PWY
superpathway of photosynthetic hydrogen production
-
-
PWY-7731
superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli)
-
-
PWY0-166
superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis
-
-
PWY-7328
Taurine and hypotaurine metabolism
-
-
taurine biosynthesis I
-
-
PWY-5331
taurine biosynthesis II
-
-
PWY-7850
taurine biosynthesis III
-
-
PWY-8359
TCA cycle I (prokaryotic)
-
-
TCA
TCA cycle II (plants and fungi)
-
-
PWY-5690
TCA cycle III (animals)
-
-
PWY66-398
TCA cycle IV (2-oxoglutarate decarboxylase)
-
-
P105-PWY
TCA cycle V (2-oxoglutarate synthase)
-
-
PWY-6969
TCA cycle VI (Helicobacter)
-
-
REDCITCYC
TCA cycle VII (acetate-producers)
-
-
PWY-7254
TCA cycle VIII (Chlamydia)
-
-
TCA-1
teichuronic acid biosynthesis (B. subtilis 168)
-
-
PWY-7820
Terpenoid backbone biosynthesis
-
-
testosterone and androsterone degradation to androstendione (aerobic)
-
-
PWY-6943
tetrahydrofolate biosynthesis I
-
-
PWY-6614
tetrahydrofolate metabolism
-
-
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate
-
-
PWY-6613
tetrapyrrole biosynthesis I (from glutamate)
-
-
PWY-5188
tetrapyrrole biosynthesis II (from glycine)
-
-
PWY-5189
the visual cycle I (vertebrates)
-
-
PWY-6861
theobromine biosynthesis I
-
-
PWY-5039
theophylline degradation
-
-
PWY-6999
thioredoxin pathway
-
-
THIOREDOX-PWY
thiosulfate disproportionation IV (rhodanese)
-
-
PWY-5350
thymine degradation
-
-
PWY-6430
thyroid hormone biosynthesis
thyroid hormone metabolism I (via deiodination)
-
-
PWY-6260
thyroid hormone metabolism II (via conjugation and/or degradation)
-
-
PWY-6261
toluene degradation II (aerobic) (via 4-methylcatechol)
-
-
TOLUENE-DEG-3-OH-PWY
toluene degradation to 2-hydroxypentadienoate (via toluene-cis-diol)
-
-
TOLUENE-DEG-DIOL-PWY
toluene degradation to 2-hydroxypentadienoate I (via o-cresol)
-
-
TOLUENE-DEG-2-OH-PWY
trans, trans-farnesyl diphosphate biosynthesis
-
-
PWY-5123
trans-3-hydroxy-L-proline degradation
-
-
PWY-7515
traumatin and (Z)-3-hexen-1-yl acetate biosynthesis
-
-
PWY-5410
trehalose degradation I (low osmolarity)
-
-
TREDEGLOW-PWY
trehalose degradation II (cytosolic)
-
-
PWY0-1182
trehalose degradation IV
-
-
PWY-2722
trehalose degradation V
-
-
PWY-2723
trehalose degradation VI (periplasmic)
-
-
PWY0-1466
triacylglycerol degradation
-
-
LIPAS-PWY
tRNA charging
-
-
TRNA-CHARGING-PWY
tRNA methylation (yeast)
-
-
PWY-6829
tRNA processing
-
-
PWY0-1479
tRNA splicing I
-
-
PWY-6689
tRNA splicing II
-
-
PWY-7803
Tropane, piperidine and pyridine alkaloid biosynthesis
-
-
Tryptophan metabolism
-
-
tryptophan metabolism
-
-
tunicamycin biosynthesis
-
-
PWY-7821
type I lipoteichoic acid biosynthesis (S. aureus)
-
-
PWY-7817
type IV lipoteichoic acid biosynthesis (S. pneumoniae)
-
-
PWY-7818
Ubiquinone and other terpenoid-quinone biosynthesis
-
-
UDP-alpha-D-galactose biosynthesis
-
-
PWY-7344
UDP-alpha-D-glucose biosynthesis
-
-
PWY-7343
UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)
-
-
PWY-7346
UDP-GlcNAc biosynthesis
-
-
UDP-N-acetyl-D-galactosamine biosynthesis II
-
-
PWY-5514
UDP-N-acetyl-D-galactosamine biosynthesis III
-
-
PWY-8013
UDP-N-acetyl-D-glucosamine biosynthesis I
-
-
UDPNAGSYN-PWY
UDP-N-acetyl-D-glucosamine biosynthesis II
-
-
UDPNACETYLGALSYN-PWY
UMP biosynthesis I
-
-
PWY-5686
UMP biosynthesis II
-
-
PWY-7790
UMP biosynthesis III
-
-
PWY-7791
uracil degradation I (reductive)
-
-
PWY-3982
urate conversion to allantoin I
-
-
PWY-5691
urate conversion to allantoin II
-
-
PWY-7394
urate conversion to allantoin III
-
-
PWY-7849
urea degradation II
-
-
PWY-5704
UTP and CTP de novo biosynthesis
-
-
PWY-7176
UTP and CTP dephosphorylation I
-
-
PWY-7185
UTP and CTP dephosphorylation II
-
-
PWY-7177
Valine, leucine and isoleucine degradation
-
-
valproate beta-oxidation
-
-
PWY-8182
vancomycin resistance I
-
-
PWY-6454
vancomycin resistance II
-
-
PWY-6455
vanillin biosynthesis I
-
-
PWY-5665
Various types of N-glycan biosynthesis
-
-
vitamin B1 metabolism
-
-
Vitamin B6 metabolism
-
-
vitamin D3 biosynthesis
-
-
PWY-6076
vitamin D3 metabolism
-
-
wax esters biosynthesis II
-
-
PWY-5885
xanthine and xanthosine salvage
-
-
SALVPURINE2-PWY
xanthommatin biosynthesis
-
-
PWY-8249
xylitol degradation I
-
-
LARABITOLUTIL-PWY
xyloglucan degradation II (exoglucanase)
-
-
PWY-6807
zymosterol biosynthesis
-
-
PWY-6074
bile acid biosynthesis, neutral pathway
-
-
PWY-6061
bile acid biosynthesis, neutral pathway
-
-
catecholamine biosynthesis
-
-
PWY66-301
catecholamine biosynthesis
-
-
cyanate degradation
-
-
CYANCAT-PWY
folate polyglutamylation
-
-
PWY-2161
folate polyglutamylation
-
-
methylaspartate cycle
-
-
PWY-6728
methylaspartate cycle
-
-
myo-inositol biosynthesis
-
-
PWY-2301
myo-inositol biosynthesis
-
-
octane oxidation
-
-
P221-PWY
thyroid hormone biosynthesis
-
-
PWY-6241
thyroid hormone biosynthesis
-
-
urea cycle
-
-
PWY-4984
vitamin K-epoxide cycle
-
-
PWY-7999
vitamin K-epoxide cycle
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
fetal
brenda
-
-
brenda
-
posterior region above blastopore
brenda
Xalas2 expression is observed in the aortic arch near the heart and posterior condylar vein
brenda
-
brenda
-
high level
brenda
-
-
brenda
-
brenda
-
-
brenda
-
-
brenda
fetal
brenda
fetal
brenda
-
-
brenda
fetal
brenda
fetal
brenda
-
larval intestinal
brenda
Xalas2 is expressed in circulating erythrocytes
brenda
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
high activity
brenda
the enzyme Xhe2 is exclusively expressed in hatching gland cells as they first emerge at the lateral edge of the anterior neural plate, and persists in this tissue up to the tadpole stage
brenda
-
-
brenda
-
brenda
larval, primary
brenda
-
brenda
-
-
brenda
-
brenda
developing limb buds at stages 4855
brenda
-
-
brenda
facial mesenchyme
brenda
-
brenda
derived from tadpole tail
brenda
fetal
brenda
cranial nerve
brenda
-
brenda
Ddx39 is present in the ventricular region of the developing neural tube up to and including stage 48
brenda
at tailbud stage
brenda
Ddx39 message is restricted to a subpopulation of proliferating cells in the developing and regenerating optic cup
brenda
-
-
brenda
-
brenda
expression of nocturnin mRNA is confined to the clock-containing photoreceptor cell layer within the retina
brenda
-
weak activity
brenda
fetal
brenda
fetal
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
brenda
-
during early embryonic development, the expression of Xdhcr7 is first of all spatially restricted to the Spemanns organizer and later to the notochord. In both tissues, Xdhcr7 is coexpressed with Sonic hedgehog, Shh
brenda
-
brenda
-
-
brenda
-
-
brenda
fetal
brenda
-
-
brenda
-
brenda
of tadpole tail tips
brenda
fetal
brenda
-
brenda
-
exposure of the cells to blue light, but not red light, for 12 h results in more than 20fold increase of the (6-4) photolyase mRNA
brenda
myoblast cell line derived from tadpole tail
brenda
-
brenda
maximum expression of XPACE4 at the early blastula stage
brenda
-
brenda
at tailbud stage
brenda
-
caspase-9 is highly expressed in tadpole brain during metamorphosis. Caspase-9 mRNA is expressed mainly in the ventricular area, a site of neuroblast proliferation. Caspase-9, a key members of the mitochondrial death pathway, is implicated in controlling the proliferative status of neuroblasts in the metamorphosing Xenopus brain. Modification of the expression during the critical period of metamorphosis alters the outcome of metamorphic neurogenesis, resulting in a modified brain phenotype in juvenile Xenopus
brenda
fetal
brenda
isozyme type III
brenda
-
lowest expression
brenda
-
predominantly membrane-associated, bifunctional enzyme
brenda
-
-
brenda
-
MLK2 expression correlates with cell elongation and the onset of an apoptotic phase
brenda
-
brenda
-
embryonic presumptive ectoderm, Spemann organizer region, trunk organizer region and posterior ectoderm
brenda
-
3906, 134068, 209629, 210533, 210534, 210536, 210539, 210551, 210565, 210604, 391708, 491495, 532734, 644123, 660923, 661534, 661560, 661596, 662999, 663259, 668364, 668838, 669391, 679359, 700097, 707877, 732099
brenda
-
10fold lower activity in adult tissues than in eggs
brenda
fertilized
brenda
histone H2A and nucleoplasmin methylation appears late in oogenesis and is most abundant in the laid egg
brenda
-
in cytostatic-arrested M-phase
brenda
-
no changes in B-Raf activity after fertilization
brenda
-
unfertilized, high activity of DNA ligase
brenda
P22182, P26619, Q0VGW8, Q62658, Q6AX64, Q6AZU6, Q7ZTK9, Q7ZX48, Q7ZYQ9, Q8AVH2, Q91549, Q91604, Q91694, Q91738, Q9DG00, Q9DG02, Q9IAJ6
-
1202, 1906, 33624, 210551, 490318, 490358, 490649, 490666, 491434, 662053, 663849, 664724, 665050, 668838, 673856, 679081, 688799, 697225, 698805, 700349, 701647, 703374, 704082, 705910, 709057, 712098, 714800, 729543, 729793, 731352, 740979, 753381, 753386, 761483
brenda
-
504 hours old
brenda
-
cement gland, lens placode, ear vesicle, mesencephalon, rhombencephalon, lymphatic vessel and heart anlage at stage 29
brenda
cleavage stage embryos
brenda
-
coexpression of enzyme and Sonic Hedgehog, Shh, during midline development in embryo. Enzyme functions as an negative regulator in Hedghog signaling at the level or downstream of Smoothend and affects intracellular Hedgehog signaling
brenda
-
cytoplasmic dynein is the sole motor for microtubule-based ER motility throughout the early stages of development
brenda
dorsal blastopore lip
brenda
enriched in vegetal masses, with no significant asymmetrical distribution between dorsal and ventral halves
brenda
enzyme Dse is maternally expressed and exhibits partially overlapping activity with enzyme Dsel in the eyes, brain, trigeminal ganglia, neural crest, adenohypophysis, sclerotome, and dorsal endoderm. Dse is specifically expressed in the epidermis, anterior surface ectoderm, spinal nerves, notochord and dermatome, quantitative enzyme real-time PCR expression analysis of different development al stages of the embryo, overview
brenda
enzyme Dsel is maternally expressed and exhibits partially overlapping activity with enzyme Dse in the eyes, brain, trigeminal ganglia, neural crest, adenohypophysis, sclerotome, and dorsal endoderm. Dsel mRNA alone is transcribed in the spinal cord, epibranchial ganglia, prechordal mesendoderm, and myotome, quantitative enzyme real-time PCR expression analysis of different development al stages of the embryo, overview
brenda
-
enzyme is widely distributed in the embryo, from late neurulae through to late tailbud stages
brenda
expressed between the midblastula transition and gastrulation
brenda
-
expression increases at later embryonal developmental stages
brenda
expression of gene SPC7 mRNA in Xenopus laevis embryos at different developmental stages by real-time PCR expression analysis, overview
brenda
expression pattern of isozyme encoding pfk1, pfkfb1, pfkfb2, pfkfb3, and pfkfb4 genes in Xenopus laevis embryos. Gene pfkfb transcripts expression is overlapping at blastula and gastrula stages and from neurulation to tadpole stages, they display tissue-specific, complementary and dynamic developmental expression patterns. At the tailbud stage, pfkfb1 is mainly expressed in the somites and in the head. At tadpole stage 26, pfkfb1 is expressed in the somites, in the spinal cord, in the notochord and in the head, and at tadpole stage 40, pfkfb1 is expressed in head mesenchyme, the somites, the spinal cord, the pronephros and the dorsal fin
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expression pattern of isozyme encoding pfk1, pfkfb1, pfkfb2, pfkfb3, and pfkfb4 genes in Xenopus laevis embryos. Gene pfkfb transcripts expression is overlapping at blastula and gastrula stages and from neurulation to tadpole stages, they display tissue-specific, complementary and dynamic developmental expression patterns. At the tailbud stage, Pfkfb2 is not detected above background. At tadpole stage 26, pfkfb2 was expressed in the ectoderm, the neural tube and the pronephros, with a low expression in the lateral somite, and at tadpole stage 40, pfkfb2 is expressed in head mesenchyme, neural tube, pronephros and at low levels in the somites
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expression pattern of isozyme encoding pfk1, pfkfb1, pfkfb2, pfkfb3, and pfkfb4 genes in Xenopus laevis embryos. Gene pfkfb transcripts expression is overlapping at blastula and gastrula stages and from neurulation to tadpole stages, they display tissue-specific, complementary and dynamic developmental expression patterns. At the tailbud stage, pfkfb4 is expressed in the cement gland, in the spinal cord, in the somites and in the ventral blood island. At tadpole stage 26, pfkfb4 is detected in the somites and in the cement gland, and at tadpole stage 40, Pfkfb4 is expressed in the somites, the spinal cord, the notochord, the dorsal fin and the head of the embryo
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expression pattern of isozyme encoding pfk1, pfkfb1, pfkfb2, pfkfb3, and pfkfb4 genes in Xenopus laevis embryos.Gene pfkfb transcripts expression is overlapping at blastula and gastrula stages and from neurulation to tadpole stages, they display tissue-specific, complementary and dynamic developmental expression patterns. At the tailbud stage, pfkfb3 is mainly found in the spinal cord and at lower level in the notochord and in the somites. At tadpole stage 26, pfkfb3 is found in the somites and at lower levels in the spinal cord and in the notochord, and at tadpole stage 40, Pfkfb3 is expressed in the spinal cord, the notochord and the dorsal fin, and at a low level in the somites
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HtrA1 is expressed in early embryo and activated by FGF signals
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in embryonic development, isoform PHD45 expression is complementary to that of PHD28. Hypoxia-inducible factor HIF-1alpha protein level is maximal around stage 20 when expression of PHD45 disappears, while expression of PHD28 reaches a maximum at stage 20. Overexpression of the ubiquitin ligase Seven-in-Absentia homolog Siah2 decreases PHD45, but not PHD28, and causes the small-eye phenotype of Xenopus
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localized to the anterior neural plate in early neurula stage embryos. Later in development, XFGFR-2 expression is found in the eye anlagen, midbrain-hindbrain boundary and the otic vesicle
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no changes in B-Raf activity in the first embryonic cell cycles
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Notum is expressed dynamically during Xenopus embryogenesis, expression is required for head formation and neural induction. Notum functions in the prostective ectoderm
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RALDH2 activity is present in limiting levels in the early gastrula embryo
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RhoV mRNA is maternally expressed and accumulates shortly after gastrulation in the neural crest forming region. Rho functions in pathways that control neural crest cells specification
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RT-PCR, xGalnt1, -6, -7 expression throughout early and late embryonal development
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silencing of UGDH decreases glycosaminoglycan synthesis causing severe embryonic malformations because of defective gastrulation process. Overexpression of the enzyme from Xenopus laevis in human smooth muscle cells increases the accumulation of hyaluronan
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Xek mRNA is expressed at higher levels in the anterior and dorsal regions of embryonic stages 16, 24 and 37
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-
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at the gastrula stage
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-
-
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expression of wild-type stromelysin-3 leads to extracellular matrix degradation and larval epithelial cell death in the intestine. Stromelysin-3 plays a role in remodeling of extracellular matrix, as a mechanism of T3-induced apoptosis during intestinal metamorphosis
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-
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fetal
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in the ciliary marginal zone adjacent to the neural retina and within the lens epithelium, present in the anterior eye during fibroblast growth factor 2 (FGF2)-mediated retinal regeneration. Ddx39 message is restricted to a subpopulation of proliferating cells in the developing and regenerating optic cup
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-
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GelA is expressed in fibroblasts surrounding apoptotic cells of intestine and tail
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-
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marginal zone, high level in dorsal region
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RT-PCR, expression is restricted to dorsal marginal zones at embryonal stage 20
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RT-PCR, xGalnt1, -6, -7 expression in both, dorsal and ventral marginal zones at embryonal stage 20
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-
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high activity
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normal quantity of ST8Sia I_short mRNA
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traces of long form of ST8Sia mRNA together with a normal quantity of the short one
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traces of of ST8Sia I_long mRNA
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-
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atrium
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isozyme B, low content of isozyme A
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lowest activity in heart
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normal quantity of ST8Sia I_long
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predominantly membrane-associated, bifunctional enzyme
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ventricle
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-
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expression of wild-type stromelysin-3 leads to extracellular matrix degradation and larval epithelial cell death in the intestine. Stromelysin-3 plays a role in remodeling of extracellular matrix, as a mechanism of T3-induced apoptosis during intestinal metamorphosis
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GelA is expressed in fibroblasts surrounding apoptotic cells, expression of GelA is downregulated in the intestine by the end of metamorphosis when the tail is completely resorbed, and the adult intestine has formed
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highly expressed specifically in the adult progenitor/stem cells during intestinal metamorphosis
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MT1-MMP is upregulated during metamorphosis and coexpressed with MMP gelatinase A in connective tissue during both natural and thyroid-hormone-induced metamorphosis, MT1-MMP is also expressed in the longitudinal muscle cells of the metamorphosing intestine
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no measurable expression of isozyme type III
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proliferating adult stem cells of the intestine
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-
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high activity
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high level of long form of ST8Sia mRNA
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high level of ST8Sia I_long
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highest activity in kidney
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isozyme B, low content of isozyme A
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mRNA is strongly expressed in differentiated epithelial structures of the pronephric kidney
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no measurable expression of isozyme type III
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strongly expressed in the kidneys during late embryonic development
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-
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premetamorphic
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1135, 33624, 95495, 172150, 391624, 394352, 655432, 658859, 660923, 664901, 675160, 675748, 679243, 679321, 718096, 724793, 732501
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frog
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highest expression
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isozyme type III
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isozymes A and B
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traces of long form of ST8Sia mRNA together with a normal quantity of the short one
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traces of of ST8Sia I_long mRNA
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-
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high activity
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high level of long form of ST8Sia mRNA
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high level of ST8Sia I_long
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-
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hypaxial
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isozymes A and B
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low expression of ST8Sia I_short mRNA
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very low expression of short form of ST8Sia I mRNA
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weak activity
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-
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fetal
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differentiated post-mitotic neurons
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-
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RT-PCR, expression at embryonal stage 13 in anterior mesoderm and neural crest
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-
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at tailbud stage
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during early embryonic development, the expression of Xdhcr7 is first of all spatially restricted to the Spemanns organizer and later to the notochord. In both tissues, Xdhcr7 is coexpressed with Sonic hedgehog, Shh
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fetal
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P13406, P22182, P24033, P26696, P28020, P35567, Q6NUA1, Q71VB9, Q7ZYJ3, Q9ES87, Q9I935, Q9IB67
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1906, 2004, 2006, 3813, 3879, 4222, 33624, 95752, 134068, 135218, 210535, 210537, 485592, 485595, 485605, 485615, 485617, 490246, 490318, 491501, 491643, 491738, 491739, 491740, 640754, 642644, 642977, 643414, 643555, 644922, 644924, 646327, 647009, 655466, 662378, 663382, 664901, 666298, 667171, 671266, 673905, 675598, 677103, 680554, 680656, 680939, 682062, 691557, 693744, 700166, 702046, 707020, 708463, 709057, 711820, 718740, 719500, 719990, 731108, 733769, 738226, 759120
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enriched in vegetal halves, with no significant asymmetrical distribution between dorsal and ventral halves
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gene is found in the maternal RNA pool of the oocyte
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high expression level of isozyme CaM-KI LiKbeta in the neurula stage
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no changes in B-Raf activity during progesterone-induced maturation
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oocyte-specific PDK isoform
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primarily concentrated in the germinal vesicle, around 5% of the activity is detected in the cytoplasm
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stage IV
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the c-mos proto-oncogene is expressed as a maternal mRNA in oocytes and early embryos of Xenopus laevis, but its translation product pp39mos is detectable only during progesterone-induced oocyte maturation
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the cellular content of the enzyme increases significantly when stage VI oocytes are hormonally stimulated into unfertilized eggs
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the cleaved form of PC7 is present in both embryos and oocytes, PC7-like activity is not detected in oocytes
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the isozymes CaM-KIalpha is constitutively expressed through embryogenesis leading
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36950, 391708, 490216, 490648, 491099, 643421, 658859, 670221, 681330, 715488, 718096
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isozymes A and B
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-
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secretory granules
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embryo, MLK2 expression correlates with the differentiation and opening of the nephritic tubules, but not with apoptosis
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pronephric duct
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-
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activity is elevated at night and rapidly inhibited by light
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constitutively present in most retinal cell
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438569, 438573, 438576, 636364, 658859, 660923, 664901, 668827, 682261, 716946, 718096
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exudate
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marked presence of of ST8Sia I_short mRNA
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marked presence of short form of ST8Sia I mRNA
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soluble enzyme with peptidylglycine alpha-hydroxylating activity or peptidylhydroxylglycine N-C lyase activity
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soluble enzyme with peptidylglycine alpha-hydroxylating activity, AE-I
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weak activity
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-
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fetal
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-
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fetal
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mRNA expression in the brain, brachial arches, trigeminal facial ganglion, and the retina of the swimming tadpole stage of development
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ST3 has little expression in premetamorphic tadpoles, but reaches very high levels by stage 60 when cell death is at high levels in the larval epithelium. It is absent by the end of metamorphosis
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stage 62 tadpole tail
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stromelysin-3 expression, in the absence of thyroid hormone, causes significant muscle cell death in the tail of premetamorphic transgenic tadpoles. On the other hand, only relatively low levels of epidermal cell death are induced by precocious thyroid hormone expression in the tail
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4 isoenzymes: AP-1, AP-2, AP-3 and AP-4
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GelA is expressed in fibroblasts surrounding apoptotic cells, spatial localization of MT1-MMP and GelA mRNAs in the tail during natural metamorphosis, overview
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MT1-MMP is upregulated during metamorphosis
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organ culture of tadpole tail tips
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stage 62 tadpole tail
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RT-PCR, expression at embryonal stage 27 excluded from the central area of the mediolateral spinal cord containing proliferating neuronal precursors
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RT-PCR, expression at embryonal stage 27 in forebrain
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RT-PCR, expression at embryonal stage 27 in neural crest cells that migrate into heart regions, branchial arches and heart anlage
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RT-PCR, expression at embryonal stage 27 in notochord (highest in posterior regions)
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RT-PCR, expression at embryonal stage 27 in the mantle (differentiating) territory of the mediolateral spinal cord
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-
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low expression of ST8Sia I_short mRNA
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very low expression of short form of ST8Sia I mRNA
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-
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MLK2 expression from late gastrula stage/early neurula stage on
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additional information
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5 isoenzymes, one isoenzyme form is present in all tissues tested, two additional forms are expressed in oocytes, embryos, adult liver and adult brain, two further forms are restricted to larval and adult muscle
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additional information
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co-localization of MT1-MMP and GelA mRNAs during amphibian development, overview
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additional information
developmental expression of enzyme Xhe2 and its regulation by transcription factor Pax3, overview
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additional information
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differential tissue-specific expression of isozymes, distribution overview
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additional information
during gastrulation, FAK protein expression increases significantly and is detected in mesoderm, marginal zone ectoderm, and cells of the blastocoel roof
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additional information
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during mitotic cell cycle, ODC exhibits two activity peaks, one at G1/S transition and the second during G2/M transition
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additional information
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isozymes show different tissue distribution
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additional information
maternal FAK transcript is present in Xl eggs, with levels decreasing slightly through cleavage and early blastula stages. At early gastrulation, the FAK mRNA level becomes modestly elevated, followed by a steady decline through late gastrulation. The mRNA level undergoes a further drop at the neurula stage, then begins a steady increase through the tailbud and tadpole stages
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additional information
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no enzyme detected in erythrocytes
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additional information
Pfkfb enzymes are overexpressed in different cancer cell lines, like melanoma, prostate, pancreatic and gastric cancer cells and mammary gland malignant cells
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additional information
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ST3 expression during amphibian metamorphosis, strong spatiotemporal correlation of its expression with apoptosis in various organs, overview
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additional information
the enzyme is first expressed in primitive erythroid cells during primary hematopoiesis before transcription of embryonic globin and is not detected in the dorsolateral plate during secondary hematopoiesis
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additional information
the enzyme is ubiquitously expressed in various tissues
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additional information
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tissue distribution, overview
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additional information
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tissue-specific expression of MLK2, no or very low expression in liver, lung, heart, muscle, and kidney
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additional information
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variety of cultured cells and cell lines
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additional information
when analyzed in whole animals, HAL1 is expressed only during embryogenesis but not metamorphosis
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additional information
when analyzed in whole animals, HAL2 is expressed during metamorphosis but not embryogenesis
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