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TaxTree of Organism Giardia duodenalis
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EC NUMBER 
COMMENTARY 
-
preliminary BRENDA-supplied EC number
preliminary BRENDA-supplied EC number
preliminary BRENDA-supplied EC number
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
(aminomethyl)phosphonate degradation
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PWY-7805
(R)-cysteate degradation
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PWY-6642
(S)-reticuline biosynthesis I
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PWY-3581
1,3-propanediol biosynthesis (engineered)
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PWY-7385
1-butanol autotrophic biosynthesis (engineered)
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PWY-6886
2-aminoethylphosphonate degradation I
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PHOSPHONOTASE-PWY
2-deoxy-alpha-D-ribose 1-phosphate degradation
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PWY-7180
2-deoxy-D-ribose degradation I
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PWY-8060
2-hydroxypenta-2,4-dienoate degradation
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PWY-5162
3-(4-hydroxyphenyl)pyruvate biosynthesis
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PWY-5886
4-hydroxybenzoate biosynthesis I (eukaryotes)
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PWY-5754
acetate and ATP formation from acetyl-CoA II
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PWY-5535
acetylene degradation (anaerobic)
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P161-PWY
adenine and adenosine salvage I
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P121-PWY
adenine and adenosine salvage II
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PWY-6605
adenine and adenosine salvage III
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PWY-6609
adenine salvage
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PWY-6610
adenosine nucleotides degradation I
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PWY-6596
adenosine nucleotides degradation II
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SALVADEHYPOX-PWY
all-trans-farnesol biosynthesis
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PWY-6859
anaerobic energy metabolism (invertebrates, cytosol)
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PWY-7383
anandamide biosynthesis I
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PWY-8051
atromentin biosynthesis
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PWY-7518
beta-(1,4)-mannan degradation
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PWY-7456
beta-1,4-D-mannosyl-N-acetyl-D-glucosamine degradation
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PWY-7586
Bifidobacterium shunt
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P124-PWY
biotin-carboxyl carrier protein assembly
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PWY0-1264
bisabolene biosynthesis (engineered)
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PWY-7102
C4 photosynthetic carbon assimilation cycle, NAD-ME type
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PWY-7115
C4 photosynthetic carbon assimilation cycle, NADP-ME type
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PWY-241
C4 photosynthetic carbon assimilation cycle, PEPCK type
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PWY-7117
Calvin-Benson-Bassham cycle
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CALVIN-PWY
cardiolipin biosynthesis I
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PWY-5668
cardiolipin biosynthesis II
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PWY-5269
cardiolipin biosynthesis III
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PWY0-1545
CDP-6-deoxy-D-gulose biosynthesis
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PWY-8139
chitin biosynthesis
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PWY-6981
chitin degradation I (archaea)
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PWY-6855
chitin derivatives degradation
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PWY-6906
coenzyme M biosynthesis II
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PWY-6643
cytosolic NADPH production (yeast)
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PWY-7268
D-galactose degradation I (Leloir pathway)
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PWY-6317
D-galactose detoxification
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PWY-3821
dTDP-beta-L-rhamnose biosynthesis
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DTDPRHAMSYN-PWY
Entner-Doudoroff pathway I
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PWY-8004
Entner-Doudoroff pathway II (non-phosphorylative)
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NPGLUCAT-PWY
Entner-Doudoroff pathway III (semi-phosphorylative)
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PWY-2221
ethanol degradation I
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ETOH-ACETYLCOA-ANA-PWY
ethanolamine utilization
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PWY0-1477
ethene biosynthesis V (engineered)
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PWY-7124
formaldehyde assimilation I (serine pathway)
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PWY-1622
formaldehyde assimilation II (assimilatory RuMP Cycle)
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PWY-1861
formaldehyde assimilation III (dihydroxyacetone cycle)
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P185-PWY
formaldehyde oxidation I
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RUMP-PWY
GDP-alpha-D-glucose biosynthesis
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PWY-5661
GDP-mannose biosynthesis
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PWY-5659
gluconeogenesis I
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GLUCONEO-PWY
gluconeogenesis II (Methanobacterium thermoautotrophicum)
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PWY-6142
gluconeogenesis III
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PWY66-399
glucose and glucose-1-phosphate degradation
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GLUCOSE1PMETAB-PWY
glucosylglycerol biosynthesis
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PWY-7902
glycerol degradation I
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PWY-4261
glycerol degradation to butanol
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PWY-7003
glycerol-3-phosphate shuttle
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PWY-6118
glycerol-3-phosphate to cytochrome bo oxidase electron transfer
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PWY0-1561
glycerol-3-phosphate to fumarate electron transfer
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PWY0-1582
glycerol-3-phosphate to hydrogen peroxide electron transport
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PWY0-1591
glycerophosphodiester degradation
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PWY-6952
glycogen biosynthesis I (from ADP-D-Glucose)
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GLYCOGENSYNTH-PWY
glycogen biosynthesis III (from alpha-maltose 1-phosphate)
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PWY-7900
glycogen degradation I
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GLYCOCAT-PWY
glycogen degradation II
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PWY-5941
glycolysis I (from glucose 6-phosphate)
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GLYCOLYSIS
glycolysis II (from fructose 6-phosphate)
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PWY-5484
glycolysis III (from glucose)
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ANAGLYCOLYSIS-PWY
glycolysis IV
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PWY-1042
glycolysis V (Pyrococcus)
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P341-PWY
glyphosate degradation III
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PWY-7807
guanine and guanosine salvage I
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PWY-6620
guanine and guanosine salvage II
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PWY-6599
guanosine nucleotides degradation I
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PWY-6607
guanosine nucleotides degradation II
-
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PWY-6606
guanosine nucleotides degradation III
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PWY-6608
heterolactic fermentation
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P122-PWY
incomplete reductive TCA cycle
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P42-PWY
indole-3-acetate biosynthesis II
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PWY-581
indole-3-acetate biosynthesis VI (bacteria)
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TRPIAACAT-PWY
inosine 5'-phosphate degradation
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PWY-5695
isopropanol biosynthesis (engineered)
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PWY-6876
L-alanine degradation V (oxidative Stickland reaction)
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PWY-8189
L-arginine biosynthesis I (via L-ornithine)
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ARGSYN-PWY
L-arginine biosynthesis II (acetyl cycle)
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ARGSYNBSUB-PWY
L-arginine biosynthesis IV (archaea)
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PWY-7400
L-arginine degradation V (arginine deiminase pathway)
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ARGDEGRAD-PWY
L-arginine degradation XIII (reductive Stickland reaction)
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PWY-8187
L-arginine degradation XIV (oxidative Stickland reaction)
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PWY-6344
L-asparagine degradation III (mammalian)
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ASPARAGINE-DEG1-PWY-1
L-aspartate biosynthesis
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ASPARTATESYN-PWY
L-aspartate degradation I
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ASPARTATE-DEG1-PWY
L-citrulline biosynthesis
-
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CITRULBIO-PWY
L-citrulline degradation
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CITRULLINE-DEG-PWY
L-glutamate biosynthesis III
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GLUTSYNIII-PWY
L-glutamate degradation II
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GLUTDEG-PWY
L-glutamate degradation VII (to butanoate)
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GLUDEG-II-PWY
L-phenylalanine biosynthesis I
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PHESYN
L-phenylalanine degradation II (anaerobic)
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ANAPHENOXI-PWY
L-phenylalanine degradation III
-
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PWY-5079
L-phenylalanine degradation IV (mammalian, via side chain)
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PWY-6318
L-phenylalanine degradation VI (reductive Stickland reaction)
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PWY-8014
L-threonine degradation IV
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PWY-5436
L-tryptophan degradation IV (via indole-3-lactate)
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TRPKYNCAT-PWY
L-tryptophan degradation VIII (to tryptophol)
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PWY-5081
L-tryptophan degradation XIII (reductive Stickland reaction)
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PWY-8017
L-tyrosine biosynthesis I
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TYRSYN
L-tyrosine degradation I
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TYRFUMCAT-PWY
L-tyrosine degradation II
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PWY-5151
L-tyrosine degradation III
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PWY3O-4108
L-tyrosine degradation IV (to 4-methylphenol)
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PWY-7514
L-tyrosine degradation V (reductive Stickland reaction)
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PWY-8016
lactate fermentation to acetate, CO2 and hydrogen (Desulfovibrionales)
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PWY-8377
malate/L-aspartate shuttle pathway
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MALATE-ASPARTATE-SHUTTLE-PWY
methoxylated aromatic compound degradation II
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PWY-8305
methyl phomopsenoate biosynthesis
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PWY-7721
mitochondrial NADPH production (yeast)
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PWY-7269
mixed acid fermentation
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FERMENTATION-PWY
mRNA capping I
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PWY-7375
N-acetylglucosamine degradation I
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GLUAMCAT-PWY
NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde
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PWY-5653
NAD biosynthesis from nicotinamide
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NAD-BIOSYNTHESIS-III
NAD de novo biosynthesis I
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PYRIDNUCSYN-PWY
NAD de novo biosynthesis III
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PWY-8352
NAD de novo biosynthesis IV (anaerobic)
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PWY-8277
NAD phosphorylation and dephosphorylation
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NADPHOS-DEPHOS-PWY
NAD phosphorylation and transhydrogenation
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NADPHOS-DEPHOS-PWY-1
NAD salvage (plants)
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PWY-5381
NAD salvage pathway I (PNC VI cycle)
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PYRIDNUCSAL-PWY
NAD salvage pathway II (PNC IV cycle)
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PWY-7761
NAD salvage pathway III (to nicotinamide riboside)
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NAD-BIOSYNTHESIS-II
NAD salvage pathway IV (from nicotinamide riboside)
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PWY3O-4106
NAD salvage pathway V (PNC V cycle)
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PWY3O-4107
NAD(P)/NADPH interconversion
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PWY-5083
NADP biosynthesis
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PWY-8148
nitrate reduction IX (dissimilatory)
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PWY0-1581
nitrate reduction X (dissimilatory, periplasmic)
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PWY0-1584
nitrogen remobilization from senescing leaves
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PWY-6549
nucleoside and nucleotide degradation (archaea)
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PWY-5532
pentose phosphate pathway (non-oxidative branch) I
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NONOXIPENT-PWY
pentose phosphate pathway (non-oxidative branch) II
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PWY-8178
pentose phosphate pathway (oxidative branch) I
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OXIDATIVEPENT-PWY
peptidoglycan recycling I
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PWY0-1261
phosphatidylcholine acyl editing
-
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PWY-6803
phosphatidylglycerol biosynthesis I
-
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PWY4FS-7
phosphatidylglycerol biosynthesis II
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PWY4FS-8
phospholipases
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LIPASYN-PWY
photosynthetic 3-hydroxybutanoate biosynthesis (engineered)
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PWY-7218
protein citrullination
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PWY-4921
protein ubiquitination
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PWY-7511
purine nucleobases degradation II (anaerobic)
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PWY-5497
pyrimidine deoxyribonucleosides degradation
-
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PWY-7181
pyrimidine nucleobases salvage I
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PWY-7183
pyrimidine ribonucleosides degradation
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PWY0-1295
pyruvate decarboxylation to acetyl CoA III
-
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PWY-8275
pyruvate fermentation to acetate I
-
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P142-PWY
pyruvate fermentation to acetate III
-
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PWY-5483
pyruvate fermentation to acetate VI
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PWY-5538
pyruvate fermentation to acetate VII
-
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PWY-5600
pyruvate fermentation to acetone
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PWY-6588
pyruvate fermentation to butanoate
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CENTFERM-PWY
pyruvate fermentation to butanol I
-
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PWY-6583
pyruvate fermentation to ethanol I
-
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PWY-5480
pyruvate fermentation to ethanol III
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PWY-6587
pyruvate fermentation to hexanol (engineered)
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PWY-6863
reductive glycine pathway of autotrophic CO2 fixation
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PWY-8303
reductive monocarboxylic acid cycle
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PWY-5493
reductive TCA cycle I
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P23-PWY
reductive TCA cycle II
-
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PWY-5392
rosmarinic acid biosynthesis I
-
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PWY-5048
Rubisco shunt
-
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PWY-5723
sedoheptulose bisphosphate bypass
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PWY0-1517
stachyose degradation
-
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PWY-6527
starch biosynthesis
-
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PWY-622
starch degradation III
-
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PWY-6731
starch degradation V
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PWY-6737
stellatic acid biosynthesis
-
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PWY-7736
streptomycin biosynthesis
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PWY-5940
sucrose biosynthesis I (from photosynthesis)
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SUCSYN-PWY
sucrose biosynthesis II
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PWY-7238
sucrose degradation II (sucrose synthase)
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PWY-3801
sucrose degradation IV (sucrose phosphorylase)
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PWY-5384
sucrose degradation V (sucrose alpha-glucosidase)
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PWY66-373
sulfoacetaldehyde degradation IV
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PWY-8062
sulfolactate degradation III
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PWY-6638
superpathway of fermentation (Chlamydomonas reinhardtii)
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PWY4LZ-257
superpathway of glucose and xylose degradation
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PWY-6901
superpathway of glycolysis and the Entner-Doudoroff pathway
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GLYCOLYSIS-E-D
superpathway of photosynthetic hydrogen production
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PWY-7731
TCA cycle VIII (Chlamydia)
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TCA-1
teichuronic acid biosynthesis (B. subtilis 168)
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PWY-7820
trans, trans-farnesyl diphosphate biosynthesis
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PWY-5123
trehalose degradation V
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PWY-2723
triethylamine degradation
-
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PWY-7085
tRNA charging
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TRNA-CHARGING-PWY
tRNA processing
-
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PWY0-1479
tunicamycin biosynthesis
-
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PWY-7821
type I lipoteichoic acid biosynthesis (S. aureus)
-
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PWY-7817
UDP-alpha-D-glucose biosynthesis
-
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PWY-7343
UDP-N-acetyl-D-galactosamine biosynthesis I
-
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PWY-5512
UDP-N-acetyl-D-galactosamine biosynthesis II
-
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PWY-5514
UDP-N-acetyl-D-glucosamine biosynthesis I
-
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UDPNAGSYN-PWY
UDP-N-acetyl-D-glucosamine biosynthesis II
-
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UDPNACETYLGALSYN-PWY
urea cycle
UTP and CTP dephosphorylation I
-
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PWY-7185
vitamin K-epoxide cycle
urea cycle
-
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PWY-4984
vitamin K-epoxide cycle
-
-
PWY-7999
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
624, 2419, 209469, 288446, 391647, 638368, 638415, 638441, 642104, 642105, 642120, 643067, 643071, 645422, 645459, 648228, 659900, 662342, 663355, 666498, 674469, 680870, 681568, 682729, 683854, 685820, 685929, 687300, 692365, 692748, 693200, 699105, 700914, 701115, 702063, 702272, 710543, 714086, 714087, 714875, 714927, 715129, 715815, 716055, 723205, 725220, 727572, 727897, 730352, 734837, 740482, 743751, 770582, 770624, 775938
-
-
-
SwissProt
-
209460, 643409, 675121, 690186, 691091, 694062, 702288, 705598, 711372, 714686, 721189, 722165, 725902, 728705, 731020, 733043, 737392, 737765, 738071, 743942, 754195, 757592, 760117, 765499, 766726, 768807, 774206
A8B1V5, A8B2K2, A8B3D3, A8BB85, A8BBP6, A8BGX2, A8BJJ7, A8BQJ3, A8BSH8, A8BWM5, O97447, P28724, P36186, P51776, Q24982, Q27657, Q7M4I9, Q868I5, Q95WU3, Q9GQI4, V6TJK7, V6U0K4
UniProt
assemblage A isolate WB, assemblage B isolate GS/H7, and assemblage A metronidazole-resistant isolate 713M3, gene cbk
UniProt
bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase, ECs 1.1.1.49 and 3.1.1.31, respectively
UniProt
isozyme PKCbeta; WB strain, ATCC 30957, isozymes beta, delta, epsilon, theta and zeta
SwissProt
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
additional information
the enzyme expression (both at mRNA and protein levels) is regulated during encystation
the enzyme localizes at spots within the cytoplasm. This pattern changes during encystation into a diffuse localization throughout the cytoplasm of encysting cells. E1 localizes in mature cysts at cytoplasmic spots and in the cyst wall
-
2419, 209469, 638368, 638403, 663355, 671653, 680870, 681568, 690711, 699105, 705598, 714927, 722165, 725902, 727572, 727897, 738607, 759898, 760117
E1 localizes in the trophozoites in a precise pattern bound to small granules or vesicles
-
encysting trophozoite, enzyme responsible for galactosamine synthesis from glucose, induced during encystment
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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
additional information
-
during encystation ADI translocates from the cytoplasm to the nucleus
the enzyme localizes at spots within the cytoplasm, this pattern changes during encystation into a diffuse localization throughout the cytoplasm of encysting cells. E1 localizes in mature cysts at cytoplasmic spots and in the cyst wall
PKC is commonly associated with a rapid redistribution of the kinase from the cytosol to membranes
ER retention/retrieval signal KQRL
gPDI-3 has a ER retention/retrieval signal KQRL, gPDI-2 has a KRKK motif
intracellular localization pattern during cyst formation
PKC is commonly associated with a rapid redistribution of the kinase from the cytosol to membranes
-
during encystation ADI translocates from the cytoplasm to the nucleus
additional information
-
enolase is found both in the secretome and in association with the surface
-
additional information
-
mitosomes, despite their advanced state of reductive evolution have retained vestiges of presequence-dependent and -independent protein import pathways akin to those that operate in mammalian mitochondria. Targeting mtHsp70 into mitosomes no longer requires cleavable presequences, a derived feature from their mitochondrial homologues
-
additional information
subcellular localization study, during encystment PKCbeta redistributs to plasma membrane from cytosol
-
LINKS TO OTHER DATABASES (specific for Giardia duodenalis)
SILVA: 16S/18S rRNA, 23S/28S rRNA
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