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Gene ontology
Version 2014-12-22
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Details for synaptic vesicle
synaptic vesicle
Gene ontology ID
GO:0008021
GO:0008021 is linked to 6 enzymes:
Definition
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane
Comment
This term should not be confused with GO:0097547 'synaptic vesicle protein transport vesicle'. STVs and synaptic vesicles differ both functionally and morphologically. Functionally, STVs are transport vesicles that deliver synaptic vesicle proteins to synapses, while synaptic vesicles are responsible for transmitter release at synapses. Morphologically, synaptic vesicles are very homogeneous, while STVs are very heterogeneous in size and shape. STVs might be a precursor for synaptic vesicles.
Synonyms
1. docked vesicle
References
1. PMID 10099709
2. PMID 12563290
3. NIF Subcellular: sao1071221672
4. Wikipedia: Synaptic vesicle
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