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Gene ontology
Version 2014-12-22
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Details for nuclear MIS12/MIND complex
Gene ontology ID
GO:0000818
Definition
A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore of a chromosome in the nucleus. It helps to recruit outer kinetochore subunits that will bind to microtubules. Nuclear localization arises in some organisms because the nuclear envelope is not broken down during mitosis. In S. cerevisiae, it consists of at least four proteins: Mtw1p, Nnf1p, Nsl1p, and Dsn1
Synonyms
1. MIND complex
2. Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex
References
1. GOC: krc
2. GOC: se
3. PMID 14633972
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Gene ontology