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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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Details for Mis6-Sim4 complex
Gene ontology ID
GO:0031511
Definition
A protein complex that forms part of the inner centromere, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human
Synonyms
1. Mis6 centromere subcomplex
2. Mis6-Mal2-Sim4 centromere complex
3. Sim4 complex
References
1. GOC: vw
2. PMID 12719471
3. PMID 15897182
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
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Gene ontology
cellular_component is a
cellular anatomical entity is a
chromosomal region is a446 BRENDA localization in branch, click for list of all
chromosome, centromeric region is a
condensed chromosome, centromeric region is a
condensed chromosome kinetochore part of
condensed chromosome inner kinetochore part of
Mis6-Sim4 complex part of