Details for raps-insc complex
Gene ontology ID
GO:1990499
Definition
Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2)
Comment
An example of this is Insc in drome (Q9W2R4) in PMID:22171003 (inferred from physical interaction).
Synonyms
1. partner of inscuteable-inscuteable complex
2. Rapsynoid-Inscuteable complex
References
1. GOC: bhm
2. PMID 221710033. IntAct: EBI-9674411
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
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at least 1 tissue/ enzyme/ localization link in this branch
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tissue/ enzyme/ localization link to BRENDA
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