Any feedback?
Please rate this page
(ontology.php)
(0/150)

BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
use AND (NOT) or OR
use AND (NOT) or OR
restrict to BRENDA links:
Details for RNA N6-methyladenosine methyltransferase complex
Gene ontology ID
GO:0036396
Definition
A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B)
Synonyms
1. m(6)A writer complex
2. m6A methyltransferase complex
3. METTL3-METTL14-WTAP methyltransferase complex
4. MIS complex
5. Mum2, Ime4, and Slz1 complex
6. WMM complex
References
1. GOC: dgf
2. GOC: sp
3. PMID 22685417
4. PMID 24316715
5. PMID 24407421
6. PMID 29507755
7. PMID 29535189
8. PMID 29547716
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
cellular_component is a
intracellular is a81 BRENDA localization in branch, click for list of all
methyltransferase complex part of15 BRENDA localization in branch, click for list of all
RNA N6-methyladenosine methyltransferase complex is a