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Gene ontology
Version 2014-12-22
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Details for ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing
Gene ontology ID
GO:0035796
Definition
A complex for the transport of metabolites into the cell, consisting of 4 subunits: a transmembrane substrate-binding protein (known as the S component), and an energy-coupling module that comprises two ATP-binding proteins (known as the A and A' components) and a transmembrane protein (known as the T component). Transport of the substrate across the membrane is driven by the hydrolysis of ATP
Comment
The ECF-type transporters differs from other types of ABC transporters because the substrate-binding subunit lies integral to the membrane.
Synonyms
1. ATP-binding cassette (ABC) transporter complex, ECF-type
2. energy coupling factor (ECF)-type ABC transporter
3. energy-coupling factor transporter
References
1. PMID 18931129
2. PMID 20972419
3. PMID 21135102
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